Escherichia coli K-12 substr. MG1655 Compound: potassium cyanide

Synonyms: KCN, kalium cyanid

Superclasses: a saltan organic salt

Chemical Formula: K(CN)

Molecular Weight: 65.116 Daltons

Salt Constituents: cyanide, K+

Unification Links: ChEBI:33191, ChemSpider:8681, PubChem:9032

Enzymes inhibited by potassium cyanide, sorted by the type of inhibition, are:

Inhibitor (Mechanism unknown) of: nitrate reductase [Iobbi87], ubiquinol oxidase (H+-transporting) [Kita84], 3'-nucleotidase [Anraku64a], galactarate dehydratase [Blumenthal66, Blumenthal64], cytochrome bd-I terminal oxidase [Kita84a], glycolate oxidase [Lord72], 2',3'-cyclic nucleotide 2'-phosphodiesterase [Anraku64a]


Anraku64a: Anraku Y (1964). "A new cyclic phosphodiesterase having a 3'-nucleotidase activity from Escherichia coli B. I. Purification and some properties of the enzyme." J Biol Chem 1964;239(10):3412-3419. PMID: 14245396

Blumenthal64: Blumenthal HJ, Jepson T (1964). "Asymmetric dehydration of galactarate by bacterial galactarate dehydratase." Biochem Biophys Res Commun 1964;17(3);282-7. PMID: 4285952

Blumenthal66: Blumenthal, HJ, Jepson, T "Galactarate Dehydrase." Methods in Enzymology 9:665-669 (1966).

Iobbi87: Iobbi C, Santini CL, Bonnefoy V, Giordano G (1987). "Biochemical and immunological evidence for a second nitrate reductase in Escherichia coli K12." Eur J Biochem 1987;168(2);451-9. PMID: 3311749

Kita84: Kita K, Konishi K, Anraku Y (1984). "Terminal oxidases of Escherichia coli aerobic respiratory chain. I. Purification and properties of cytochrome b562-o complex from cells in the early exponential phase of aerobic growth." J Biol Chem 1984;259(5);3368-74. PMID: 6365921

Kita84a: Kita K, Konishi K, Anraku Y (1984). "Terminal oxidases of Escherichia coli aerobic respiratory chain. II. Purification and properties of cytochrome b558-d complex from cells grown with limited oxygen and evidence of branched electron-carrying systems." J Biol Chem 1984;259(5);3375-81. PMID: 6321507

Lord72: Lord JM (1972). "Glycolate oxidoreductase in Escherichia coli." Biochim Biophys Acta 1972;267(2);227-37. PMID: 4557653

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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