Escherichia coli K-12 substr. MG1655 Compound: Cu+

Synonyms: Cu(I), cuprous ion, cuprous copper

Superclasses: an iona cationan inorganic cationa monovalent inorganic cation
an ionan inorganic ionan inorganic cationa monovalent inorganic cation

Component of:

Chemical Formula: HCu

Molecular Weight: 63.546 Daltons

Monoisotopic Molecular Weight: 63.9374261321 Daltons


InChI: InChI=1S/Cu/q+1


Unification Links: ChEBI:49552, ChemSpider:94614, IAF1260:2323762, PubChem:104815

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): 0.0

Reactions known to consume the compound:

Not in pathways:
2 Cu+[periplasm] + 2 H+[periplasm] + oxygen[periplasm] → 2 Cu2+[periplasm] + 2 H2O[periplasm]

In Reactions of unknown directionality:

Not in pathways:
Cu2+ + NADH = Cu+ + NAD+
ComR + Cu+ = ComR-Cu(I)
CueR + Cu+ = CueR-Cu(I)

In Transport reactions:
Cu+[cytosol] + ATP + H2O → Cu+[periplasm] + ADP + phosphate + H+,
Cu+[cytosol] + H+[periplasm]Cu+[extracellular space] + H+[cytosol],
an ion[periplasm]an ion[extracellular space]

Enzymes inhibited by Cu+, sorted by the type of inhibition, are:

Inhibitor (Mechanism unknown) of: phosphoglucomutase [Joshi64]

This compound has been characterized as a cofactor or prosthetic group of the following enzymes: NADH:ubiquinone oxidoreductase, NADH cupric reductase


Joshi64: Joshi JG, Handler P (1964). "Phosphoglucomutase. I. Purification and properties of phosphoglucomutase from Escherichia coli." J. Biol. Chem. 239:2741-2751. PMID: 14216423

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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