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Escherichia coli K-12 substr. MG1655 Compound: Cu+

Synonyms: Cu(I), cuprous ion, cuprous copper

Superclasses: an ion a cation

Component of:
ComR-Cu(I)
CueR-Cu(I)

Chemical Formula: Cu

Molecular Weight: 63.546 Daltons

Monoisotopic Molecular Weight: 62.9296011 Daltons

SMILES: [Cu+]

InChI: InChI=1S/Cu/q+1

InChIKey: InChIKey=VMQMZMRVKUZKQL-UHFFFAOYSA-N

Unification Links: ChEBI:49552 , ChemSpider:94614 , IAF1260:2323762 , PubChem:104815

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): 0.0

Reactions known to consume the compound:

Not in pathways:
4 Cu+[periplasmic space] + 4 H+[periplasmic space] + oxygen[periplasmic space] → 4 Cu2+[periplasmic space] + 2 H2O[periplasmic space]

In Reactions of unknown directionality:

Not in pathways:
Cu2+ + NADH = Cu+ + NAD+ + H+
ComR + Cu+ = ComR-Cu(I)
CueR + Cu+ = CueR-Cu(I)

In Transport reactions:
Cu+[cytosol] + ATP + H2O → Cu+[periplasmic space] + ADP + phosphate + H+ ,
Cu+[cytosol] + H+[periplasmic space]Cu+[extracellular space] + H+[cytosol]

Enzymes inhibited by Cu+, sorted by the type of inhibition, are:

Inhibitor (Mechanism unknown) of: phosphoglucomutase [Joshi64a]

This compound has been characterized as a cofactor or prosthetic group of the following enzymes: NADH:ubiquinone oxidoreductase , NADH cupric reductase


References

Joshi64a: Joshi JG, Handler P (1964). "Phosphoglucomutase. I. Purification and properties of phosphoglucomutase from Escherichia coli." J. Biol. Chem. 239:2741-2751. PMID: 14216423


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, BIOCYC13A.