Escherichia coli K-12 substr. MG1655 Compound: K+

Synonyms: potassium, potassium ion

Superclasses: an iona cationan inorganic cationa monovalent inorganic cation
an ionan inorganic ionan inorganic cationa monovalent inorganic cation

Component of:
dipotassium phosphate
potassium cyanide
monopotassium phosphate
potassium chloride
potassium sulfate

Molecular Weight: 39.098 Daltons

Monoisotopic Molecular Weight: 38.9637069 Daltons


InChI: InChI=1S/K/q+1


Unification Links: ChEBI:29103, ChemSpider:791, HMDB:HMDB00586, IAF1260:34349, KEGG:C00238, MetaboLights:MTBLC29103, PubChem:813

Standard Gibbs Free Energy of Formation (ΔfG in kcal/mol): 0.0

In Transport reactions:
K+[periplasm] + H+[periplasm]K+[cytosol] + H+[cytosol],
K+[periplasm] + ATP + H2O → K+[cytosol] + ADP + phosphate + H+,
K+[cytosol] + H+[periplasm]K+[periplasm] + H+[cytosol],
an ion[periplasm]an ion[extracellular space]

Enzymes activated by K+, sorted by the type of activation, are:

Activator (Non-allosteric) of: citrate synthase Activator (Mechanism unknown) of: fructose bisphosphate aldolase [Blom96], UDP-N-acetyl-D-mannosamine dehydrogenase [Kawamura79], RNase R [Cheng02], GTP cyclohydrolase [Schoedon92], NADH:ubiquinone oxidoreductase (H+-transporting) [Euro09a], nicotinate-mononucleotide adenylyltransferase [Dahmen67], homoserine dehydrogenase [Ogilvie75, Wedler93], UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase [Michaud90, Comment 1], UDP-N-acetylenolpyruvoylglucosamine reductase [Dhalla95, Shapiro12, Comment 2], guanylate kinase [Oeschger66], RNase D exonuclease [Ghosh78], tryptophanase [Tokushige89, HogbergRaibaud75, Comment 3], thiamin kinase, glyoxylate carboligase [Gupta66, Comment 4], malate dehydrogenase [Sanwal69, Spina70, Bologna07, Brown81], RNase BN exoribonuclease [Callahan00], IMP dehydrogenase [Kerr00, Comment 5], carbamoyl phosphate synthetase [Thoden99], exopolyphosphatase [Akiyama93, Comment 6], trehalose-6-phosphate synthase [Giaever88, Comment 7], thiamine monophosphate kinase [Nishino72, Comment 8], glycerol dehydrogenase [Tang79, Comment 9]

Enzymes inhibited by K+, sorted by the type of inhibition, are:

Inhibitor (Mechanism unknown) of: 6-phosphofructokinase [Baez13], guanosine-5'-triphosphate, 3'-diphosphate pyrophosphatase [Keasling93], aspartate semialdehyde dehydrogenase [Hegeman70, Helmward89], ribonucleoside-triphosphate reductase [Eliasson92, Comment 10], dihydrofolate reductase [Baccanari75], dTMP kinase [Helmward89]

This compound has been characterized as a cofactor or prosthetic group of the following enzymes: pyridoxal kinase, selenide, water dikinase, tRNA nucleotidyltransferase, homoserine kinase, D-malate dehydrogenase (decarboxylating), inosine kinase, guanosine kinase, 10-formyltetrahydrofolate:L-methionyl-tRNAfMet N-formyltransferase, ribokinase, pantothenate synthetase, pyruvate kinase, methionine adenosyltransferase, UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase, pyruvate kinase, ribonucleoside-triphosphate reductase, rhamnulose-1-phosphate aldolase, folylpoly-γ-glutamate synthetase, ribonuclease, CTP:2,3,4-saturated L-phosphatidate cytidylyltransferase, phosphoribosylformylglycinamide cyclo-ligase

This compound has been characterized as an alternative substrate of the following enzymes: L-proline:H+ symporter

In Growth Media: PMA carbon source test + ser, Gutnick minimal salts medium base + N-acetylneuraminate, PMA carbon source test + N-acetylneuraminate, PMA carbon source test + D-mannose, PMA carbon source test + D-fructose, MOPS medium with 2% glycerol, M63 medium with 2% glycerol, MOPS medium with 2% glucose, MOPS medium with 0.4% glucose, MOPS medium base, Neidhardt EZ rich defined medium, Gutnick minimal salts medium base + ethyl-4-aminobutyrate, PMA carbon source test + putrescine, Davis and Mingioli glucose minimal medium, Davis and Mingioli medium A, Gutnick minimal salts medium base + xanthosine, Gutnick minimal salts medium base + xanthine, Gutnick minimal salts medium base + putrescine, Gutnick minimal salts medium base + orotate, Gutnick minimal salts medium base + N-acetyl-D-glucosamine, Gutnick minimal salts medium base + trp, Gutnick minimal salts medium base + thr, Gutnick minimal salts medium base + L-ornithine, Gutnick minimal salts medium base + glt, Gutnick minimal salts medium base + gln, Gutnick minimal salts medium base + asp, Gutnick minimal salts medium base + asn, Gutnick minimal salts medium base + arg, Gutnick minimal salts medium base + inosine, Gutnick minimal salts medium base + gly, Gutnick minimal salts medium base + D-glucosamine, Gutnick minimal salts medium base + D-alanine, Gutnick minimal salts medium base + cyanate, Gutnick minimal salts medium base + 2'-deoxyinosine, Gutnick minimal salts medium base, PMA sulfur source test + 3-sulfinoalanine, PMA nitrogen source test + L-2-aminopentanoate, PMA carbon source test + citramalate, AB medium with 0.4% acetate, AB medium with 0.2% glucose, M63 medium with 2% glucose, M9 medium with 2% glycerol, M9 medium with 1% glycerol, M9 medium with 0.4% glucose, LB enriched, PMA carbon source test + methyl-β -D-glucoside, M9 medium base, PMA carbon source test + 3-hydroxybutanoate, PMA carbon source test + 2-hydroxybutyrate, ATCC medium 57, PMA carbon source test + Tween 80, PMA carbon source test + Tween 40, PMA carbon source test + Tween 20, PMA carbon source test + trans-4-hydroxy-L-proline, PMA carbon source test + gelatin, PMA carbon source test + L-galactono-1,4-lactone, PMA carbon source test + α-hydroxyglutarate-γ-lactone, PMA nitrogen source test + N-acetyl-D,L-glutamate, PMA carbon source test + melezitose, PMA carbon source test + D-ribono-1,4-lactone, PMA carbon source test + salicylate, PMA carbon source test + methyl-α-D-galactopyranoside, PMA nitrogen source test + D-mannosamine, PMA nitrogen source test + ala-gln, PMA nitrogen source test + ala-asp, PMA nitrogen source test + D,L-lactamide, PMA carbon source test + methyl D-lactate, PMA carbon source test + bromosuccinate, PMA carbon source test + gly-asp, PMA nitrogen source test + ala-his, PMA nitrogen source test + L-Ala-L-Glu, PMA nitrogen source test + ala-thr, PMA nitrogen source test + ala-leu, PMA carbon source test + turanose, PMA carbon source test + ala-gly, PMA nitrogen source test + gln, PMA nitrogen source test + gly-asn, PMA carbon source test + diacetyl, PMA carbon source test + lactitol, PMA nitrogen source test + methionine-alanine dipeptide, PMA nitrogen source test + gly-met, PMA sulfur source test + gly-met, PMA sulfur source test + cysteinylglycine, PMA phosphorus source test + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, PMA phosphorus source test + 3-phospho-D-glycerate, PMA phosphorus source test + 2-phospho-D-glycerate, PMA phosphorus source test + cyclic-AMP, PMA phosphorus source test + 3'-adenosine monophosphate, PMA phosphorus source test + phosphinate, PMA sulfur source test + 4-aminobenzenesulfonate, PMA sulfur source test + ethionine, PMA sulfur source test + sulfolane, PMA sulfur source test + methanesulfonate, PMA sulfur source test + isethionate, PMA sulfur source test + 1-butanesulfonate, PMA sulfur source test + hypotaurine, PMA sulfur source test + taurine, PMA sulfur source test + taurocholate, PMA sulfur source test + lipoamide, PMA sulfur source test + 1-thio-β-D-glucose, PMA sulfur source test + thiourea, PMA sulfur source test + djenkolate, PMA sulfur source test + L-Methionine sulfone, PMA sulfur source test + L-methionine S-oxide, PMA sulfur source test + N-acetyl-DL-methionine, PMA sulfur source test + D-methionine, PMA sulfur source test + met, PMA sulfur source test + glutathione, PMA sulfur source test + lanthionine, PMA sulfur source test + L-cystathionine, PMA sulfur source test + S-methyl-L-cysteine, PMA sulfur source test + N-acetyl-L-cysteine, PMA sulfur source test + cysteamine, PMA sulfur source test + (R)-cysteate, PMA sulfur source test + D-cysteine, PMA sulfur source test + cys, PMA sulfur source test + dithiophosphate, PMA sulfur source test + thiophosphate, PMA sulfur source test + tetrathionate, PMA sulfur source test + thiosulfate, PMA sulfur source test + sulfate, PMA phosphorus source test + thymidine 3'5'-cyclic monophosphate, PMA phosphorus source test + dTMP, PMA phosphorus source test + thymidine 3'-monophosphate, PMA phosphorus source test + methylenediphosphonate, PMA phosphorus source test + 2-aminoethylphosphonate, PMA phosphorus source test + phosphonoacetate, PMA phosphorus source test + phosphoryl-ethanolamine, PMA phosphorus source test + phosphoryl-choline, PMA phosphorus source test + creatine-phosphate, PMA phosphorus source test + O-phospho-L-tyrosine, PMA phosphorus source test + O-phospho-D-tyrosine, PMA phosphorus source test + uridine 3'5'-cyclic monophosphate, PMA phosphorus source test + uridine 2'3'-cyclic monophosphate, PMA phosphorus source test + UMP, PMA phosphorus source test + uridine 3'-monophosphate, PMA phosphorus source test + uridine 2'-monophosphate, PMA phosphorus source test + L-threonine O-3-phosphate, PMA phosphorus source test + 3-phospho-L-serine, PMA phosphorus source test + O-phospho-D-serine, PMA phosphorus source test + N-phospho-L-arginine, PMA phosphorus source test + cysteamine S-phosphate, PMA phosphorus source test + D-mannose 6-phosphate, PMA phosphorus source test + α-D-mannose 1-phosphate, PMA phosphorus source test + 3',5'-cyclic CMP, PMA phosphorus source test + cytidine 2',3'-cyclic monophosphate, PMA phosphorus source test + CMP, PMA phosphorus source test + cytidine-3'-monophosphate, PMA phosphorus source test + cytidine 2'-monophosphate, PMA phosphorus source test + 6-phospho-D-gluconate, PMA phosphorus source test + D-glucosamine-6-phosphate, PMA phosphorus source test + 2-deoxy-D-glucose 6-phosphate, PMA phosphorus source test + D-glucose-6-phosphate, PMA phosphorus source test + α-D-glucose 1-phosphate, PMA phosphorus source test + 2-phosphoglycolate, PMA phosphorus source test + phosphoenolpyruvate, PMA phosphorus source test + cyclic-GMP, PMA phosphorus source test + guanosine 2',3'-cyclic monophosphate, PMA phosphorus source test + GMP, PMA phosphorus source test + guanosine 3'-monophosphate, PMA phosphorus source test + guanosine 2'-monophosphate, PMA phosphorus source test + carbamoyl-phosphate, PMA phosphorus source test + glycerol 2-phosphate, PMA phosphorus source test + sn-glycerol-3-phosphate, PMA phosphorus source test + dithiophosphate, PMA phosphorus source test + thiophosphate, PMA phosphorus source test + adenosine 2'3'-cyclic monophosphate, PMA phosphorus source test + AMP, PMA phosphorus source test + adenosine 2'-monophosphate, PMA phosphorus source test + triethyl phosphate, PMA phosphorus source test + PPPi, PMA phosphorus source test + trimetaphosphate, PMA phosphorus source test + diphosphate, PMA phosphorus source test + phosphate, PMA nitrogen source test + glycyl-L-glutamate, PMA nitrogen source test + ala-gly, PMA nitrogen source test + 5-aminopentanoate, PMA nitrogen source test + 2-aminocaprylate, PMA nitrogen source test + 6-aminohexanoate, PMA nitrogen source test + 4-aminobutyrate, PMA nitrogen source test + 2-aminobutyrate, PMA nitrogen source test + parabanate, PMA nitrogen source test + allantoin, PMA nitrogen source test + alloxan, PMA nitrogen source test + urate, PMA nitrogen source test + xanthosine, PMA nitrogen source test + xanthine, PMA nitrogen source test + inosine, PMA nitrogen source test + uridine, PMA nitrogen source test + uracil, PMA nitrogen source test + thymidine, PMA nitrogen source test + thymine, PMA nitrogen source test + guanosine, PMA nitrogen source test + guanine, PMA nitrogen source test + cytosine, PMA nitrogen source test + cytidine, PMA nitrogen source test + adenosine, PMA nitrogen source test + adenine, PMA nitrogen source test + N-acetyl-D-mannosamine, PMA nitrogen source test + an N-acetyl-D-galactosamine, PMA nitrogen source test + N-acetyl-D-glucosamine, PMA nitrogen source test + galactosamine, PMA nitrogen source test + D-glucosamine, PMA nitrogen source test + glucuronamide, PMA nitrogen source test + formamide, PMA nitrogen source test + acetamide, PMA nitrogen source test + tyramine, PMA nitrogen source test + 2-phenylethylamine, PMA nitrogen source test + histamine, PMA nitrogen source test + agmatine, PMA nitrogen source test + putrescine, PMA nitrogen source test + ethylenediamine, PMA nitrogen source test + ethanolamine, PMA nitrogen source test + ethylamine, PMA nitrogen source test + butylamine, PMA nitrogen source test + n-amylamine, PMA nitrogen source test + methylamine, PMA nitrogen source test + hydroxylamine, PMA nitrogen source test + 5-oxoproline, PMA nitrogen source test + 2-phthalimidoglutarate, PMA nitrogen source test + L-ornithine, PMA nitrogen source test + L-homoserine, PMA nitrogen source test + L-citrulline, PMA nitrogen source test + D-valine, PMA nitrogen source test + D-serine, PMA nitrogen source test + D-lysine, PMA nitrogen source test + D-glutamate, PMA nitrogen source test + D-aspartate, PMA nitrogen source test + D-asparagine, PMA nitrogen source test + D-alanine, PMA nitrogen source test + val, PMA nitrogen source test + tyr, PMA nitrogen source test + trp, PMA nitrogen source test + thr, PMA nitrogen source test + ser, PMA nitrogen source test + pro, PMA nitrogen source test + phe, PMA nitrogen source test + met, PMA nitrogen source test + lys, PMA nitrogen source test + leu, PMA nitrogen source test + ile, PMA nitrogen source test + his, PMA nitrogen source test + gly, PMA nitrogen source test + gln, PMA nitrogen source test + glt, PMA nitrogen source test + cys, PMA nitrogen source test + asp, PMA nitrogen source test + asn, PMA nitrogen source test + arg, PMA nitrogen source test + ala, PMA nitrogen source test + biuret, PMA nitrogen source test + urea, PMA nitrogen source test + nitrate, PMA nitrogen source test + nitrite, PMA nitrogen source test + ammonia, PMA carbon source test + acetoin, PMA carbon source test + (R,R)-2,3-butanediol, PMA carbon source test + dihydroxyacetone, PMA carbon source test + 1-(4-hydroxyphenyl)-2-aminoethanol, PMA carbon source test + sec-butylamine, PMA carbon source test + a D,L-carnitine, PMA carbon source test + val, PMA carbon source test + 5-oxoproline, PMA carbon source test + phe, PMA carbon source test + L-ornithine, PMA carbon source test + met, PMA carbon source test + lys, PMA carbon source test + leu, PMA carbon source test + ile, PMA carbon source test + L-homoserine, PMA carbon source test + his, PMA carbon source test + gly, PMA carbon source test + arg, PMA carbon source test + N-acetyl-L-glutamate, PMA carbon source test + L-alanine amide, PMA carbon source test + acetamide, PMA carbon source test + L-tartrate, PMA carbon source test + D-tartrate, PMA carbon source test + succinamate, PMA carbon source test + sorbate, PMA carbon source test + sebacate, PMA carbon source test + L-quinate, PMA carbon source test + 3-oxalomalate, PMA carbon source test + oxalate, PMA carbon source test + melibionate, PMA carbon source test + malonate, PMA carbon source test + 5-dehydro-D-gluconate, PMA carbon source test + itaconate, PMA carbon source test + 2-ketopentanoate, PMA carbon source test + 4-hydroxybutyrate, PMA carbon source test + 4-hydroxybenzoate, PMA carbon source test + D-glucosamine, PMA carbon source test + citraconate, PMA carbon source test + hexanoate, PMA carbon source test + caprate, PMA carbon source test + 2-butanoate, PMA carbon source test + 5-aminopentanoate, PMA carbon source test + 4-aminobutyrate, PMA carbon source test + N-acetyl -D- glucosaminitol, PMA carbon source test + D-xylitol, PMA carbon source test + D-tagatose, PMA carbon source test + stachyose, PMA carbon source test + L-sorbose, PMA carbon source test + sedoheptulose anhydride, PMA carbon source test + salicin, PMA carbon source test + raffinose, PMA carbon source test + palatinose, PMA carbon source test + 1-O-methyl-β-D-xylopyranose, PMA carbon source test + methyl α-D-mannopyranoside, PMA carbon source test + 1-O-methyl-β-D-glucuronate, PMA carbon source test + 3-O-methyl-d-glucose, PMA carbon source test + methyl-β-D-galactoside, PMA carbon source test + methyl α-D-glucoside, PMA carbon source test + maltitol, PMA carbon source test + L-glucose, PMA carbon source test + β-gentiobiose, PMA carbon source test + 3-O-β-D-galactopyranosyl-D-arabinose, PMA carbon source test + D-fucose, PMA carbon source test + erythritol, PMA carbon source test + 2'-deoxyribose, PMA carbon source test + hydroquinone-O-β-D-glucopyranoside, PMA carbon source test + L-arabitol, PMA carbon source test + D-arabitol, PMA carbon source test + D-arabinose, PMA carbon source test + (R)-amygdalin, PMA carbon source test + D-allose, PMA carbon source test + an N-acetyl-D-galactosamine, PMA carbon source test + a pectin, PMA carbon source test + a mannan, PMA carbon source test + a laminaran, PMA carbon source test + an inulin, PMA carbon source test + glycogen, PMA carbon source test + a dextrin, PMA carbon source test + γ-cyclodextrin, PMA carbon source test + β-cyclodextrin, PMA carbon source test + α-cyclodextrin, PMA carbon source test + chondroitin sulfate C, PMA carbon source test + ethanolamine, PMA carbon source test + 2-phenylethylamine, PMA carbon source test + D-galacturonate, PMA carbon source test + pyruvate, PMA carbon source test + glucuronamide, PMA carbon source test + β-L-lyxopyranose, PMA carbon source test + D-psicose, PMA carbon source test + tyramine, PMA carbon source test + 3-hydroxyphenylacetate, PMA carbon source test + 4-hydroxyphenylacetate, PMA carbon source test + glycylproline, PMA carbon source test + (S)-malate, PMA carbon source test + (R)-malate, PMA carbon source test + methyl pyruvate, PMA carbon source test + mono-methyl hydrogen succinate, PMA carbon source test + N-acetyl-D-mannosamine, PMA carbon source test + acetoacetate, PMA carbon source test + ala, PMA carbon source test + thr, PMA carbon source test + propane-1,2,3-tricarboxylate, PMA carbon source test + glycyl-L-glutamate, PMA carbon source test + inosine, PMA carbon source test + cellobiose, PMA carbon source test + glyoxylate, PMA carbon source test + glycolate, PMA carbon source test + D-galactarate, PMA carbon source test + propionate, PMA carbon source test + fumarate, PMA carbon source test + D-threonine, PMA carbon source test + myo-inositol, PMA carbon source test + citrate, PMA carbon source test + adenosine, PMA carbon source test + deoxyadenosine, PMA carbon source test + maltotriose, PMA carbon source test + D-ribitol, PMA carbon source test + D-fructose-6-phosphate, PMA carbon source test + α-D-glucose 1-phosphate, PMA carbon source test + meso-tartrate, PMA carbon source test + gln, PMA carbon source test + uridine, PMA carbon source test + sucrose, PMA carbon source test + lactulose, PMA carbon source test + lactose, PMA carbon source test + 2-oxobutanoate, PMA carbon source test + 2-oxoglutarate, PMA carbon source test + L-1,2-propanediol, PMA carbon source test + glucosaminate, PMA carbon source test + D-aspartate, PMA carbon source test + asn, PMA carbon source test + thymidine, PMA carbon source test + melibiose, PMA carbon source test + maltose, PMA carbon source test + α-D-glucose, PMA carbon source test + acetate, PMA carbon source test + L-rhamnose, PMA carbon source test + D-ribose, PMA carbon source test + (RS)-malate, PMA carbon source test + D-galactono-1,4-lactone, PMA carbon source test + D-glucose-6-phosphate, PMA carbon source test + glt, PMA carbon source test + D-mannitol, PMA carbon source test + formate, PMA carbon source test + (S)-lactate, PMA carbon source test + D-xylose, PMA carbon source test + sn-glycerol-3-phosphate, PMA carbon source test + D-gluconate, PMA carbon source test + D-glucuronate, PMA carbon source test + L-fucose, PMA carbon source test + glycerol, PMA carbon source test + D-sorbitol, PMA carbon source test + D-serine, PMA carbon source test + D-galactitol, PMA carbon source test + trehalose, PMA carbon source test + D-alanine, PMA carbon source test + pro, PMA carbon source test + asp, PMA carbon source test + D-galactose, PMA carbon source test + succinate, PMA carbon source test + D-glucarate, PMA carbon source test + N-acetyl-D-glucosamine, PMA carbon source test + L-arabinose, Bochner defined minimal medium without phosphorous, Bochner defined minimal medium without sulfur, Bochner defined minimal medium without nitrogen, Bochner defined minimal medium without carbon, Bochner defined minimal medium, Davis and Mingioli Modified medium, M56 medium, AB medium base, M63 medium base


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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