Escherichia coli K-12 substr. MG1655 Compound: L-allo-threonine

Superclasses: an acid all carboxy acids a carboxylate an amino acid an alpha amino acid a non-standard alpha amino acid DL-allothreonine
an amino acid or its derivative an amino acid an alpha amino acid a non-standard alpha amino acid DL-allothreonine

Chemical Formula: C4H9NO3

Molecular Weight: 119.12 Daltons

Monoisotopic Molecular Weight: 119.0582431604 Daltons

L-<I>allo</I>-threonine compound structure

SMILES: CC(O)C([N+])C(=O)[O-]

InChI: InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3-/m0/s1


Unification Links: CAS:28954-12-3 , ChEBI:58585 , HMDB:HMDB04041 , IAF1260:45952 , KEGG:C05519 , MetaboLights:MTBLC58585 , NCI:206283 , PubChem:6995276

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -124.34

Reactions known to produce the compound:

Not in pathways:
a carboxylic ester + H2O → an alcohol + a carboxylate + H+
an aldehyde + NADP+ + H2O → a carboxylate + NADPH + 2 H+
an acyl phosphate + H2O → a carboxylate + phosphate + H+
an acyl-CoA + H2O → a carboxylate + coenzyme A + H+
a 1-acyl 2-lyso-phosphatidylcholine + H2O → a carboxylate + sn-glycero-3-phosphocholine + H+

Reactions known to both consume and produce the compound:

Not in pathways:
L-allo-threonine ↔ glycine + acetaldehyde

Not in pathways:
DL-allothreonine ↔ acetaldehyde + glycine

In Reactions of unknown directionality:

Not in pathways:
L-allo-threonine + NADP+ = aminoacetone + CO2 + NADPH
L-allo-threonine + NADP+ = 2-amino-3-oxobutanoate + NADPH + H+

Not in pathways:
a 5-L-glutamyl-[peptide][periplasmic space] + an amino acid[periplasmic space] = a 5-L-glutamyl-amino acid[periplasmic space] + a peptide[periplasmic space]

Not in pathways:
a 2-acyl 1-lyso-phosphatidylcholine + H2O = a carboxylate + sn-glycero-3-phosphocholine + H+
an aldehyde[periplasmic space] + FAD[periplasmic space] + H2O[periplasmic space] = a carboxylate[periplasmic space] + FADH2[periplasmic space]

Enzymes inhibited by L-allo-threonine, sorted by the type of inhibition, are:

Inhibitor (Mechanism unknown) of: D-serine ammonia-lyase [Labow66]

This compound has been characterized as an alternative substrate of the following enzymes: 3-hydroxy acid dehydrogenase


Labow66: Labow R, Robinson WG (1966). "Crystalline D-serine dehydrase." J Biol Chem 1966;241(5);1239-43. PMID: 5327101

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Thu Jul 30, 2015, biocyc14.