Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Compound: methanol

Synonyms: MetOH, carbinol, MeOH, methyl alcohol, wood alcohol

Superclasses: an alcohol a short-chain alcohol

Chemical Formula: CH4O

Molecular Weight: 32.042 Daltons

Monoisotopic Molecular Weight: 32.026214750499996 Daltons

SMILES: CO

InChI: InChI=1S/CH4O/c1-2/h2H,1H3

InChIKey: InChIKey=OKKJLVBELUTLKV-UHFFFAOYSA-N

Unification Links: CAS:67-56-1 , ChEBI:17790 , ChemSpider:864 , HMDB:HMDB01875 , KEGG:C00132 , MetaboLights:MTBLC17790 , PubChem:887

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -41.92

Reactions known to produce the compound:

8-amino-7-oxononanoate biosynthesis I :
a pimeloyl-[acp] methyl ester + H2O → a pimeloyl-[acp] + methanol + H+

Not in pathways:
Tsrglu-Me + H2O → methanol + Tsrglu
Trgglu-Me + H2O → methanol + Trgglu
Targlu-Me + H2O → methanol + Targlu
Tapglu-Me + H2O → methanol + Tapglu
methyl β-D-glucoside 6-phosphate + H2O → β-D-glucose 6-phosphate + methanol
a [protein]-L-glutamate-O5-methyl-ester + H2O → a [protein]-α-L-glutamate + methanol + H+

β-D-glucuronide and D-glucuronate degradation :
a β-D-glucuronoside + H2O → D-glucopyranuronate + an alcohol

glycerophosphodiester degradation :
a glycerophosphodiester + H2O → an alcohol + sn-glycerol 3-phosphate + H+


an alcohol + NAD+ + H2O ← an organic hydroperoxide + NADH + H+
an N-acetyl-β-D-hexosaminide + H2O → an N-acetyl-β-D-hexosamine + an alcohol
a carboxylic ester + H2O → an alcohol + a carboxylate + H+
an acetic ester + H2O → an alcohol + acetate + H+
an organic hydroperoxide + a reduced thioredoxin → an alcohol + an oxidized thioredoxin + H2O
a phosphate monoester[periplasmic space] + H2O[periplasmic space]an alcohol[periplasmic space] + phosphate[periplasmic space]
a phosphate monoester[periplasmic space] + H2O[periplasmic space]an alcohol[periplasmic space] + phosphate[periplasmic space]

In Reactions of unknown directionality:

Not in pathways:
an alcohol + NADP+ = an aldehyde + NADPH + H+

In Transport reactions:
methanol[cytosol]methanol[periplasmic space]

Enzymes activated by methanol, sorted by the type of activation, are:

Activator (Mechanism unknown) of: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Leppik76]


References

Leppik76: Leppik RA, Young IG, Gibson F (1976). "Membrane-associated reactions in ubiquinone biosynthesis in Escherichia coli. 3-Octaprenyl-4-hydroxybenzoate carboxy-lyase." Biochim Biophys Acta 1976;436(4);800-10. PMID: 782527


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, biocyc14.