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Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
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Escherichia coli K-12 substr. MG1655 Compound Class: a pyrimidine 2'-deoxyribonucleoside

Superclasses: a nucleic acid component a nucleoside a 2'-deoxynucleoside
a nucleic acid component a nucleoside a pyrimidine nucleoside
an organic heterocyclic compound an organonitrogen heterocyclic compound a diazine a pyrimidine a pyrimidine nucleoside

Instances:
2'-deoxycytidine ,
2'-deoxyuridine ,
thymidine

SMILES: C1(C([a pyrimidine base])OC(CO)C(O)1)

Unification Links: BRENDA:274087 , ChEBI:68472

Reactions known to consume the compound:

Not in pathways:
a pyrimidine nucleoside + H2O + H+ → a pyrimidine base + D-ribofuranose

Reactions known to produce the compound:

Not in pathways:
a 2'-deoxyribonucleoside 3'-monophosphate[periplasmic space] + H2O[periplasmic space]a 2'-deoxynucleoside[periplasmic space] + phosphate[periplasmic space]
a 2'-deoxyribonucleoside 5'-monophosphate + H2O → a 2'-deoxynucleoside + phosphate


a nucleoside 5'-monophosphate[periplasmic space] + H2O[periplasmic space]a nucleoside[periplasmic space] + phosphate[periplasmic space]

In Transport reactions:
a nucleoside[extracellular space]a nucleoside[periplasmic space] ,
a nucleoside[periplasmic space] + H+[periplasmic space]a nucleoside[cytosol] + H+[cytosol]

Enzymes inhibited by a pyrimidine 2'-deoxyribonucleoside, sorted by the type of inhibition, are:

Inhibitor (Mechanism unknown) of: acid phosphatase / phosphotransferase [Thaller97]

Credits:
Created 23-Oct-2009 by Kothari A , SRI International


References

Thaller97: Thaller MC, Schippa S, Bonci A, Cresti S, Rossolini GM (1997). "Identification of the gene (aphA) encoding the class B acid phosphatase/phosphotransferase of Escherichia coli MG1655 and characterization of its product." FEMS Microbiol Lett 1997;146(2);191-8. PMID: 9011040


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sun Nov 23, 2014, biocyc14.