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Escherichia coli K-12 substr. MG1655 Compound: D-ribulose 5-phosphate

Synonyms: ribulose-5P, D-ribulose-5-P, ribulose-5-P

Superclasses: all carbohydratesa carbohydratea glycana carbohydrate derivativea sugar phosphatea pentose phosphatea pentose 5-phosphateL(or D)-ribulose 5-phosphate
all carbohydratesa carbohydratea glycana carbohydrate derivativea sugar phosphatea sugar 5-phosphatea pentose 5-phosphateL(or D)-ribulose 5-phosphate


Chemical Formula: C5H9O8P

Molecular Weight: 228.1 Daltons

Monoisotopic Molecular Weight: 230.01915383989999 Daltons

D-ribulose 5-phosphate compound structure

SMILES: C(C(C(C(CO)=O)O)O)OP([O-])([O-])=O

InChI: InChI=1S/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h4-6,8-9H,1-2H2,(H2,10,11,12)/p-2/t4-,5+/m1/s1

InChIKey: InChIKey=FNZLKVNUWIIPSJ-UHNVWZDZSA-L

Unification Links: CAS:4151-19-3, ChEBI:58121, ChemSpider:20015724, HMDB:HMDB00618, IAF1260:34237, KEGG:C00199, MetaboLights:MTBLC58121, PubChem:21144996

Standard Gibbs Free Energy of Formation (ΔfG in kcal/mol): -393.5

Reactions known to consume the compound:

flavin biosynthesis I (bacteria and plants) :
D-ribulose 5-phosphate → 1-deoxy-L-glycero-tetrulose 4-phosphate + formate + H+

Not in pathways:
D-ribulose 5-phosphate + NADH + H+ → 1-deoxy-D-xylulose 5-phosphate + NAD+ + H2O

Not in pathways:
a sugar phosphate + H2O → a sugar + phosphate

Reactions known to produce the compound:

pentose phosphate pathway (oxidative branch) :
D-gluconate 6-phosphate + NADP+D-ribulose 5-phosphate + CO2 + NADPH

Reactions known to both consume and produce the compound:

CMP-3-deoxy-D-manno-octulosonate biosynthesis :
aldehydo-D-arabinose 5-phosphate ↔ D-ribulose 5-phosphate

pentose phosphate pathway (non-oxidative branch) :
D-ribose 5-phosphate ↔ D-ribulose 5-phosphate
D-ribulose 5-phosphate ↔ D-xylulose 5-phosphate

In Transport reactions:
a [PTS enzyme I]-Nπ-phospho-L-histidine + a sugar[periplasm] → a [PTS enzyme I]-L-histidine + a sugar phosphate[cytosol]

Enzymes inhibited by D-ribulose 5-phosphate, sorted by the type of inhibition, are:

Inhibitor (Mechanism unknown) of: 6-phosphogluconate dehydrogenase

This compound has been characterized as an alternative substrate of the following enzymes: allulose-6-phosphate 3-epimerase


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Wed Jan 2, 2002, biocyc12.