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Metabolic Modeling Tutorial
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discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
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Escherichia coli K-12 substr. MG1655 Polypeptide: UhpC-glucose-6-P



Gene: uhpC Accession Numbers: EG11053 (EcoCyc), b3667, ECK3658

Synonyms: regulatory protein UhpC-glucose-6-phosphate, modified regulatory protein UhpC

Regulation Summary Diagram: ?

Alternative forms of UhpC-glucose-6-P: inner membrane protein sensing glucose-6-phosphate (extended summary available)

Gene Citations: [Park07, Weston87, Weston88, Merkel92]

Map Position: [3,845,328 <- 3,846,647] (82.88 centisomes)
Length: 1320 bp / 439 aa

Molecular Weight: 48.388 kD (from nucleotide sequence)

Unification Links: ASAP:ABE-0011990 , CGSC:15449 , EchoBASE:EB1046 , EcoGene:EG11053 , OU-Microarray:b3667 , PortEco:uhpC , RefSeq:NP_418123 , RegulonDB:EG11053

Relationship Links: Pfam:IN-FAMILY:PF07690

In Paralogous Gene Group: 550 (2 members)

In Reactions of unknown directionality:

Not in pathways:
β-D-glucose 6-phosphate + UhpC = UhpC-glucose-6-P

Gene-Reaction Schematic: ?

Genetic Regulation Schematic: ?

MultiFun Terms: cell structure membrane
metabolism carbon utilization carbon compounds


Gene Local Context (not to scale): ?

Transcription Units:

Notes:

History:
Peter D. Karp on Wed Jan 18, 2006:
Gene right-end position adjusted based on analysis performed in the 2005 E. coli annotation update [Riley06 ].
10/20/97 Gene b3667 from Blattner lab Genbank (v. M52) entry merged into EcoCyc gene EG11053; confirmed by SwissProt match.


References

Merkel92: Merkel TJ, Nelson DM, Brauer CL, Kadner RJ (1992). "Promoter elements required for positive control of transcription of the Escherichia coli uhpT gene." J Bacteriol 1992;174(9);2763-70. PMID: 1569008

Park07: Park JH, Lee KH, Kim TY, Lee SY (2007). "Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulation." Proc Natl Acad Sci U S A 104(19);7797-802. PMID: 17463081

Riley06: Riley M, Abe T, Arnaud MB, Berlyn MK, Blattner FR, Chaudhuri RR, Glasner JD, Horiuchi T, Keseler IM, Kosuge T, Mori H, Perna NT, Plunkett G, Rudd KE, Serres MH, Thomas GH, Thomson NR, Wishart D, Wanner BL (2006). "Escherichia coli K-12: a cooperatively developed annotation snapshot--2005." Nucleic Acids Res 34(1);1-9. PMID: 16397293

Weston87: Weston LA, Kadner RJ (1987). "Identification of uhp polypeptides and evidence for their role in exogenous induction of the sugar phosphate transport system of Escherichia coli K-12." J Bacteriol 1987;169(8);3546-55. PMID: 3038843

Weston88: Weston LA, Kadner RJ (1988). "Role of uhp genes in expression of the Escherichia coli sugar-phosphate transport system." J Bacteriol 1988;170(8);3375-83. PMID: 3042748


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Fri Nov 28, 2014, biocyc14.