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discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Polypeptide: predicted lipoprotein



Gene: yifL Accession Numbers: G0-10471 (EcoCyc), b4558, ECK3803

Regulation Summary Diagram: ?

Summary:
No information about this protein was found by a literature search conducted on March 1, 2013.

Citations: [ParadisBleau14]

Locations: inner membrane

Map Position: [3,992,545 -> 3,992,748] (86.05 centisomes)
Length: 204 bp / 67 aa

Molecular Weight of Polypeptide: 7.177 kD (from nucleotide sequence)

Unification Links: ASAP:ABE-0285079 , EchoBASE:EB2257 , EcoGene:EG12353 , EcoliWiki:b4558 , PortEco:yifL , Pride:P0ADN6 , Protein Model Portal:P0ADN6 , RefSeq:YP_588473 , RegulonDB:G0-10471 , String:511145.b4558 , UniProt:P0ADN6

Relationship Links: Prosite:IN-FAMILY:PS51257

GO Terms:

Cellular Component: GO:0005886 - plasma membrane Inferred by computational analysis [UniProtGOA11, UniProtGOA11a]
GO:0016020 - membrane Inferred by computational analysis [UniProtGOA11a]

Gene Class: UNCLASSIFIED

Essentiality data for yifL knockouts: ?

Growth Medium Growth? T (°C) O2 pH Osm/L Growth Observations
LB enriched Yes 37 Aerobic 6.95   Yes [Gerdes03, Comment 1]
LB Lennox Yes 37 Aerobic 7   Yes [Baba06, Comment 2]
M9 medium with 1% glycerol Yes 37 Aerobic 7.2 0.35 Yes [Joyce06, Comment 3]
MOPS medium with 0.4% glucose Yes 37 Aerobic 7.2 0.22 Yes [Baba06, Comment 2]

Credits:
Last-Curated ? 01-Mar-2013 by Keseler I , SRI International


Sequence Features

Feature Class Location Citations Comment
Signal-Sequence 1 -> 19
[UniProt10]
UniProt: Non-Experimental Qualifier: potential;
Lipid-Binding-Site 20
[UniProt10]
UniProt: N-palmitoyl cysteine; Non-Experimental Qualifier: potential;
Chain 20 -> 67
[UniProt09]
UniProt: Uncharacterized lipoprotein yifL;
Sequence-Conflict 60 -> 67
[Glaser92, UniProt10a]
Alternate sequence: DGPSQVNY → MVHPR; UniProt: (in Ref. 1);


Gene Local Context (not to scale): ?

Transcription Unit:

Notes:

History:
Peter D. Karp on Thu Jan 19, 2006:
Existence of this gene was inferred by analysis performed in the 2005 E. coli annotation update [Riley06 ].


References

Baba06: Baba T, Ara T, Hasegawa M, Takai Y, Okumura Y, Baba M, Datsenko KA, Tomita M, Wanner BL, Mori H (2006). "Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection." Mol Syst Biol 2;2006.0008. PMID: 16738554

Gerdes03: Gerdes SY, Scholle MD, Campbell JW, Balazsi G, Ravasz E, Daugherty MD, Somera AL, Kyrpides NC, Anderson I, Gelfand MS, Bhattacharya A, Kapatral V, D'Souza M, Baev MV, Grechkin Y, Mseeh F, Fonstein MY, Overbeek R, Barabasi AL, Oltvai ZN, Osterman AL (2003). "Experimental determination and system level analysis of essential genes in Escherichia coli MG1655." J Bacteriol 185(19);5673-84. PMID: 13129938

Glaser92: Glaser P., Sismeiro O., Danchin A. (1992). Data submission to EMBL/GenBank/DDBJ databases on 1992-06.

Joyce06: Joyce AR, Reed JL, White A, Edwards R, Osterman A, Baba T, Mori H, Lesely SA, Palsson BO, Agarwalla S (2006). "Experimental and computational assessment of conditionally essential genes in Escherichia coli." J Bacteriol 188(23);8259-71. PMID: 17012394

ParadisBleau14: Paradis-Bleau C, Kritikos G, Orlova K, Typas A, Bernhardt TG (2014). "A genome-wide screen for bacterial envelope biogenesis mutants identifies a novel factor involved in cell wall precursor metabolism." PLoS Genet 10(1);e1004056. PMID: 24391520

Riley06: Riley M, Abe T, Arnaud MB, Berlyn MK, Blattner FR, Chaudhuri RR, Glasner JD, Horiuchi T, Keseler IM, Kosuge T, Mori H, Perna NT, Plunkett G, Rudd KE, Serres MH, Thomas GH, Thomson NR, Wishart D, Wanner BL (2006). "Escherichia coli K-12: a cooperatively developed annotation snapshot--2005." Nucleic Acids Res 34(1);1-9. PMID: 16397293

UniProt09: UniProt Consortium (2009). "UniProt version 15.8 released on 2009-10-01 00:00:00." Database.

UniProt10: UniProt Consortium (2010). "UniProt version 2010-07 released on 2010-06-15 00:00:00." Database.

UniProt10a: UniProt Consortium (2010). "UniProt version 2010-11 released on 2010-11-02 00:00:00." Database.

UniProtGOA11: UniProt-GOA (2011). "Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries."

UniProtGOA11a: UniProt-GOA (2011). "Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries."

Other References Related to Gene Regulation

Richaud88: Richaud C, Printz C (1988). "Nucleotide sequence of the dapF gene and flanking regions from Escherichia coli K12." Nucleic Acids Res 16(21);10367. PMID: 3057443


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, BIOCYC13B.