Escherichia coli K-12 substr. MG1655 Polypeptide: small membrane protein

Gene: yohP Accession Numbers: G0-10652 (EcoCyc), b4679, ECK4494

Regulation Summary Diagram: ?

Regulation summary diagram for yohP

The yohP open reading frame was predicted based on the presence of a ribosome binding site in an intergenic region. YohP contains a predicted transmembrane segment, and the protein can be found in the membrane fraction [Hemm08, Fontaine11]. YohP is highly expressed during stationary phase [Hemm08]. Topology assays using GFP and PhoA fusion proteins suggest that YohP may have a dual orientation within the membrane [Fontaine11].

Locations: inner membrane

Map Position: [2,227,004 -> 2,227,087] (48.0 centisomes, 173°)
Length: 84 bp / 27 aa

Molecular Weight of Polypeptide: 3.092 kD (from nucleotide sequence)

Unification Links: EcoGene:EG14484 , PortEco:yohP , RegulonDB:G0-10652 , String:511145.b4679 , UniProt:C1P609

GO Terms:

Cellular Component: GO:0005886 - plasma membrane Inferred from experiment Inferred by computational analysis [UniProtGOA11, UniProtGOA11a, Fontaine11]
GO:0016020 - membrane Inferred by computational analysis [UniProtGOA11a, Hemm08]
GO:0016021 - integral component of membrane Inferred by computational analysis [UniProtGOA11a]

Gene Class: ORFs Conserved-ORFs

Created 30-Jan-2009 by Keseler I , SRI International
Curated 30-Jan-2009 by Keseler I , SRI International
Last-Curated ? 16-Aug-2011 by Mackie A , Macquarie University

Gene Local Context (not to scale): ?

Gene local context diagram

The database does not contain any information about transcription units for this gene.


Fontaine11: Fontaine F, Fuchs RT, Storz G (2011). "Membrane localization of small proteins in Escherichia coli." J Biol Chem 286(37);32464-74. PMID: 21778229

Hemm08: Hemm MR, Paul BJ, Schneider TD, Storz G, Rudd KE (2008). "Small membrane proteins found by comparative genomics and ribosome binding site models." Mol Microbiol 70(6);1487-501. PMID: 19121005

UniProtGOA11: UniProt-GOA (2011). "Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries."

UniProtGOA11a: UniProt-GOA (2011). "Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Fri Jul 31, 2015, biocyc14.