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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
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Escherichia coli K-12 substr. MG1655 Polypeptide: QseC sensory histidine kinase - phosphorylated



Gene: qseC Accession Numbers: EG12658 (EcoCyc), b3026, ECK3017

Synonyms: ygiY, QseC-Phis246

Regulation Summary Diagram: ?

Alternative forms of QseC sensory histidine kinase - phosphorylated: QseC sensory histidine kinase (summary available)

Summary:
This is the phosphorylated form of QseC - the sensor histidine kinase of the QseBC two-component signal transduction system.

Gene Citations: [Sperandio02, Clarke05]

Locations: inner membrane

Map Position: [3,168,506 -> 3,169,855] (68.29 centisomes)
Length: 1350 bp / 449 aa

Unification Links: ASAP:ABE-0009938 , EchoBASE:EB2845 , EcoGene:EG12658 , OU-Microarray:b3026 , PortEco:qseC , RegulonDB:EG12658

In Paralogous Gene Group: 122 (29 members)

Reactions known to consume the compound:

QseBC Two-Component Signal Transduction System, quorum sensing related :
QseB + QseC sensory histidine kinase - phosphorylated[inner membrane] → QseB-Pasp51 + QseC[inner membrane]

Reactions known to produce the compound:

QseBC Two-Component Signal Transduction System, quorum sensing related :
QseC[inner membrane] + ATP → QseC sensory histidine kinase - phosphorylated[inner membrane] + ADP

Gene-Reaction Schematic: ?

Genetic Regulation Schematic: ?

GO Terms:

Cellular Component: GO:0005886 - plasma membrane

MultiFun Terms: information transfer protein related posttranslational modification
regulation type of regulation posttranscriptional covalent modification, demodification, maturation
regulation type of regulation transcriptional level complex regulation two component regulatory systems (external signal)

Credits:
Created 21-Apr-2010 by Mackie A , Macquarie University


Sequence Features

Feature Class Location Citations Comment State
Phosphorylation-Modification 246
[UniProt13]
UniProt: Phosphohistidine; by autocatalysis; Non-Experimental Qualifier: by similarity.
Modified


Gene Local Context (not to scale): ?

Transcription Units:

Notes:

History:
1/26/1998 (pkarp) Merged genes G7576/b3026 and EG12658/ygiO


References

Clarke05: Clarke MB, Sperandio V (2005). "Transcriptional autoregulation by quorum sensing Escherichia coli regulators B and C (QseBC) in enterohaemorrhagic E. coli (EHEC)." Mol Microbiol 58(2);441-55. PMID: 16194231

Sperandio02: Sperandio V, Torres AG, Kaper JB (2002). "Quorum sensing Escherichia coli regulators B and C (QseBC): a novel two-component regulatory system involved in the regulation of flagella and motility by quorum sensing in E. coli." Mol Microbiol 43(3);809-21. PMID: 11929534

UniProt13: UniProt Consortium (2013). "UniProt version 2013-08 released on 2013-08-01 00:00:00." Database.

Other References Related to Gene Regulation

Clarke05a: Clarke MB, Sperandio V (2005). "Transcriptional regulation of flhDC by QseBC and sigma (FliA) in enterohaemorrhagic Escherichia coli." Mol Microbiol 57(6);1734-49. PMID: 16135237

Guckes13: Guckes KR, Kostakioti M, Breland EJ, Gu AP, Shaffer CL, Martinez CR, Hultgren SJ, Hadjifrangiskou M (2013). "Strong cross-system interactions drive the activation of the QseB response regulator in the absence of its cognate sensor." Proc Natl Acad Sci U S A 110(41);16592-7. PMID: 24062463


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sun Dec 21, 2014, BIOCYC13B.