Escherichia coli K-12 substr. MG1655 Polypeptide: QseC sensory histidine kinase - phosphorylated

Gene: qseC Accession Numbers: EG12658 (EcoCyc), b3026, ECK3017

Synonyms: ygiY, QseC-Phis246

Regulation Summary Diagram: ?

Regulation summary diagram for qseC

Alternative forms of QseC sensory histidine kinase - phosphorylated: QseC sensory histidine kinase (summary available)

This is the phosphorylated form of QseC - the sensor histidine kinase of the QseBC two-component signal transduction system.

Gene Citations: [Sperandio02, Clarke05]

Locations: inner membrane

Map Position: [3,168,506 -> 3,169,855] (68.29 centisomes, 246°)
Length: 1350 bp / 449 aa

Unification Links: ASAP:ABE-0009938 , EchoBASE:EB2845 , EcoGene:EG12658 , OU-Microarray:b3026 , PortEco:qseC , RegulonDB:EG12658

In Paralogous Gene Group: 122 (29 members)

Reactions known to consume the compound:

QseBC Two-Component Signal Transduction System, quorum sensing related :
QseB + QseC sensory histidine kinase - phosphorylated → QseB-Pasp51 + QseC

Reactions known to produce the compound:

QseBC Two-Component Signal Transduction System, quorum sensing related :
QseC + ATP → QseC sensory histidine kinase - phosphorylated + ADP

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Genetic Regulation Schematic: ?

Genetic regulation schematic for qseC

GO Terms:

Cellular Component: GO:0005886 - plasma membrane

MultiFun Terms: information transfer protein related posttranslational modification
regulation type of regulation posttranscriptional covalent modification, demodification, maturation
regulation type of regulation transcriptional level complex regulation two component regulatory systems (external signal)

Created 21-Apr-2010 by Mackie A , Macquarie University

Sequence Features

Protein sequence of QseC sensory histidine kinase - phosphorylated with features indicated

Feature Class Location Citations Comment State
Phosphorylation-Modification 246
UniProt: Phosphohistidine; by autocatalysis; Non-Experimental Qualifier: by similarity.

Gene Local Context (not to scale): ?

Gene local context diagram

Transcription Units:

Transcription-unit diagram

Transcription-unit diagram


1/26/1998 (pkarp) Merged genes G7576/b3026 and EG12658/ygiO


Clarke05: Clarke MB, Sperandio V (2005). "Transcriptional autoregulation by quorum sensing Escherichia coli regulators B and C (QseBC) in enterohaemorrhagic E. coli (EHEC)." Mol Microbiol 58(2);441-55. PMID: 16194231

Sperandio02: Sperandio V, Torres AG, Kaper JB (2002). "Quorum sensing Escherichia coli regulators B and C (QseBC): a novel two-component regulatory system involved in the regulation of flagella and motility by quorum sensing in E. coli." Mol Microbiol 43(3);809-21. PMID: 11929534

UniProt13: UniProt Consortium (2013). "UniProt version 2013-08 released on 2013-08-01 00:00:00." Database.

Other References Related to Gene Regulation

Clarke05a: Clarke MB, Sperandio V (2005). "Transcriptional regulation of flhDC by QseBC and sigma (FliA) in enterohaemorrhagic Escherichia coli." Mol Microbiol 57(6);1734-49. PMID: 16135237

Guckes13: Guckes KR, Kostakioti M, Breland EJ, Gu AP, Shaffer CL, Martinez CR, Hultgren SJ, Hadjifrangiskou M (2013). "Strong cross-system interactions drive the activation of the QseB response regulator in the absence of its cognate sensor." Proc Natl Acad Sci U S A 110(41);16592-7. PMID: 24062463

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Tue Oct 6, 2015, biocyc13.