Escherichia coli K-12 substr. MG1655 Polypeptide: RcsC sensory histidine kinase - asp875 phosphorylated

Gene: rcsC Accession Numbers: EG10822 (EcoCyc), b2218, ECK2211

Synonyms: RcsC-Pasp875

Regulation Summary Diagram: ?

Regulation summary diagram for rcsC

Alternative forms of RcsC sensory histidine kinase - asp875 phosphorylated:
RcsC sensory histidine kinase (extended summary available)
RcsC sensory histidine kinase - his 479 phosphorylated (summary available)

This is a phosphorylated form of RcsC - the sensory histidine kinase of the RcsCDB two-component signal transduction system.

Gene Citations: [Mukhopadhyay97]

Locations: inner membrane

Map Position: [2,315,049 <- 2,317,850] (49.9 centisomes, 180°)
Length: 2802 bp / 933 aa

Unification Links: ASAP:ABE-0007336 , CGSC:17974 , EchoBASE:EB0815 , EcoGene:EG10822 , OU-Microarray:b2218 , PortEco:rcsC , RegulonDB:EG10822

In Paralogous Gene Group: 121 (40 members) , 122 (29 members)

Reactions known to consume the compound:

RcsCDB Two-Component Signal Transduction System :
RcsD + RcsC-Pasp → RcsD-Phis + RcsC

Reactions known to produce the compound:

RcsCDB Two-Component Signal Transduction System :
RcsC-Phis[inner membrane]RcsC-Pasp[inner membrane]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

GO Terms:

Cellular Component: GO:0005886 - plasma membrane

MultiFun Terms: cell structure capsule (M and K antigens)
cell structure membrane
cell structure surface antigens (ECA, O antigen of LPS)
information transfer protein related posttranslational modification
metabolism biosynthesis of macromolecules (cellular constituents) colanic acid (M antigen)
regulation type of regulation posttranscriptional covalent modification, demodification, maturation
regulation type of regulation transcriptional level complex regulation two component regulatory systems (external signal)

Created 02-Aug-2010 by Mackie A , Macquarie University

Sequence Features

Protein sequence of RcsC sensory histidine kinase - asp875 phosphorylated with features indicated

Feature Class Location Citations Comment State
Phosphorylation-Modification 479
UniProt: Phosphohistidine; by autocatalysis; Non-Experimental Qualifier: by similarity.
4-aspartylphosphate-Modification 875
UniProt: 4-aspartylphosphate; Non-Experimental Qualifier: by similarity.

Gene Local Context (not to scale): ?

Gene local context diagram

Transcription Unit:

Transcription-unit diagram


10/20/97 Gene b2218 from Blattner lab Genbank (v. M52) entry merged into EcoCyc gene EG10822; confirmed by SwissProt match.


Mukhopadhyay97: Mukhopadhyay S, Schellhorn HE (1997). "Identification and characterization of hydrogen peroxide-sensitive mutants of Escherichia coli: genes that require OxyR for expression." J Bacteriol 1997;179(2);330-8. PMID: 8990283

UniProt11a: UniProt Consortium (2011). "UniProt version 2011-11 released on 2011-11-22 00:00:00." Database.

UniProt13: UniProt Consortium (2013). "UniProt version 2013-08 released on 2013-08-01 00:00:00." Database.

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Sat Oct 10, 2015, BIOCYC14A.