Escherichia coli K-12 substr. MG1655 RNA: RyeA small RNA

Gene: ryeA Accession Numbers: G0-8865 (EcoCyc), b4432, ECK1838

Synonyms: sraC, psrA8, tkpe79, IS091

Superclasses: Misc-RNAs

Regulation Summary Diagram: ?

Regulation summary diagram for ryeA

RyeA and SraC are reported to be the same RNA [Gottesman01]. SraC is reported to be a small RNA of approximately 234-249 nt in length [Argaman01], and RyeA and RyeB are reported to be small RNAs of approximately 275 nt and 100 nt in length, respectively (and shorter species have also been detected) [Wassarman01]. RyeA and RyeB are encoded within the same inter-ORF region of the genome [Wassarman01], with RyeB being complementary to an internal segment of RyeA [Vogel03].

Interactions between RyeA RNA and Hfq protein and between RyeB RNA and Hfq have been detected [Wassarman01].

RyeA RNA is subject to RNase III cleavage which coincides with the appearance of RyeB at the onset of stationary phase [Argaman01, Vogel03].

RyeA RNA has similarity to sequences from Salmonella, Yersinia pestis, and Klebsiella pneumoniae [Argaman01].

Sra: "small RNA" [Argaman01]

PsrA: "predicted small RNA" [Argaman01]

Ryx: "RNA of unknown function at X position (10 minute) in the genome" [Wassarman01].

Regulation has been described [Argaman01, Wassarman01]. The half life of SraC in stationary phase is 2 minutes [Vogel03].

Reviews: [Gottesman01, Hershberg03]

Citations: [Chen02a]

Map Position: [1,921,090 -> 1,921,338] (41.41 centisomes, 149°)
Length: 249 bp

Unification Links: ASAP:ABE-0047252 , EchoBASE:EB4516 , EcoGene:EG31146 , EcoliWiki:b4432 , PortEco:ryeA , RegulonDB:G0-8865

MultiFun Terms: information transfer RNA related

Gene Local Context (not to scale): ?

Gene local context diagram

Transcription Unit:

Transcription-unit diagram



Argaman01: Argaman L, Hershberg R, Vogel J, Bejerano G, Wagner EG, Margalit H, Altuvia S (2001). "Novel small RNA-encoding genes in the intergenic regions of Escherichia coli." Curr Biol 11(12);941-50. PMID: 11448770

Chen02a: Chen S, Lesnik EA, Hall TA, Sampath R, Griffey RH, Ecker DJ, Blyn LB (2002). "A bioinformatics based approach to discover small RNA genes in the Escherichia coli genome." Biosystems 65(2-3);157-77. PMID: 12069726

Gottesman01: Gottesman S, Storz G, Rosenow C, Majdalani N, Repoila F, Wassarman KM (2001). "Small RNA regulators of translation: mechanisms of action and approaches for identifying new small RNAs." Cold Spring Harb Symp Quant Biol 66;353-62. PMID: 12762038

Hershberg03: Hershberg R, Altuvia S, Margalit H (2003). "A survey of small RNA-encoding genes in Escherichia coli." Nucleic Acids Res 31(7);1813-20. PMID: 12654996

Vogel03: Vogel J, Bartels V, Tang TH, Churakov G, Slagter-Jager JG, Huttenhofer A, Wagner EG (2003). "RNomics in Escherichia coli detects new sRNA species and indicates parallel transcriptional output in bacteria." Nucleic Acids Res 31(22);6435-43. PMID: 14602901

Wassarman01: Wassarman KM, Repoila F, Rosenow C, Storz G, Gottesman S (2001). "Identification of novel small RNAs using comparative genomics and microarrays." Genes Dev 15(13);1637-51. PMID: 11445539

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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