Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
twitter

Escherichia coli K-12 substr. MG1655 RNA: rrfG 5S ribosomal RNA



Gene: rrfG Accession Numbers: EG30075 (EcoCyc), b2588, ECK2586

Synonyms: rrnG

Superclasses: 5S rRNA

Regulation Summary Diagram: ?

Summary:
The 5S and 23S rRNAs are the RNA components of the large subunit (50S subunit) of the E. coli ribosome.

There are seven ribosomal RNA (rRNA) operons, called rrnA, rrnB, rrnC, rrnD, rrnE, rrnG, and rrnH [Neidhardt96]. Each operon contains a 16S rRNA gene, a 23S rRNA gene, and a 5S rRNA gene (except the rrnD operon, which contains two 5S rRNA genes) interspersed with various tRNA genes [Neidhardt96]. Regarding nomenclature, "rrs" genes encode 16S rRNAs, "rrl" genes encode 23S rRNAs, and "rrf" genes encode 5S rRNAs [Neidhardt96].

The sequence and structure of the 5S rRNA has been described [Brownlee67, Boedtker67, Monier68, Cantor68, Cramer68, Raacke68, Aubert68, Reynier69, Richards69, Lewis70, Vigne71, Richards72, Fox75, Marshall77, Bear77, Vigne77, Weidner77, Lewis77, Chen78, Luoma78, Wagner78, Apirion78, Rabin79, Appel79, Jagadeeswaran80, Kao80, Burns80, Marshall80, Bohm81, Fanning81, Ramstein81, Peattie81, Douthwaite81, Speek82, Hancock82, Fox82, Pieler82, Kime82, Matveev, Stiege82, Delihas82, Luoma82, Matveeva, Kime83, Kime83a, Nazar83, Moore83, Erdmann83, Leontis84, Pieler84, Kime84, Goringer84, Christensen85, Pieler85, Muller86, Leontis86, Leontis86a, Goringer86, Leontis86b, Lorenz87, Gewirth87, Nagano88, Davis89, Zhang89, Zhang89a, Lorenz, Metelev90, Johnson91, Nazar91, Brunel91, White92, Ciesiolka92, Ciesiollka92, Zhong94, Dallas, Barciszewska96, Grune96, Grune96a, Correll97, Dallas97, Leontis98, Shpanchenko98, Wohnert99, Stoldt99, Lu00, Iwase99, Mahara00].

The relationship of the 5S rRNA to ribosome assembly, structure, and function has been characterized [Morell68, Siddiqui68, Siddiqui69, Forget70, Feunteun71, Bellemare72, Erdmann72, Erdmann73, Delihas75, Dohme76, Schreiber79, Spierer79, Jagadeeswaran80, Kao80, Odom80, Digweed81, StofflerMeilick81, Pace82, Rohl82, Rohl82a, Pieler82, Parker83, Silberklang83, Chiam83, Tewari83, Brewer83, Dontsova94, Sergiev98, Shpanchenko98, Ostergaard98, Osswald99, Mueller00, Sergiev00].

Interactions between the 5S rRNA and ribosomal proteins have been described [Horne72, Bellemare73, Schulte75, Brosius75, Bitar75, Berger75, Chu76, Osterberg76, Bear77, Zimmermann78, Newberry78, Spierer78, Spierer78a, Douthwaite79, Garrett79, Newberry80, Fanning81, Maimets, Peattie81, Speek82, Douthwaite82, Kime83a, Moore83, Huber84, Kime84a, Christiansen85, Szymkowiak85, Leontis86a, Gewirth88, Egebjerg89, Dontsova90, Osswald90, Barciszewska96, Shpanchenko96, Stoldt99, Lu00, Okada00, Perederina02].

Interactions between the 5S rRNA and 23S rRNA have been described [Gray72, Herr75, Newberry80, Ostergaard98].

Analysis of mutations in 5S rRNA has been conducted [Pace82, Goringer84a, Goringer86a, Gewirth87a, Vester88, Gewirth88, Zhang89b, Zvereva98, Ammons99, Ammons01].

The post-transcriptional processing of the 5S rRNA has been characterized [Galibert69, Forget70a, Galibert71, Lund77, Ghora78, Ghora79, Goldblum81, Clark84, Szeberenyi84, Christiansen88, Melefors91, Georgellis92, Cormack92, Cormack93, Carpousis94, Li95, Bessarab98, Kaberdin00, Lee02, Zuo02].

Regulation has been described in detail; for a review see [Schneider03a].

Reviews [Lind, Azad79, Tanaka85, Nowotny88, Moore88, Vester88, Goringer88, Srivastava91, Barciszewska96, Barciszewska97].

Citations: [Robins68, Scott68, Jordan69, Feunteun70, Kaiser70, Doolittle70, Jarry71, Philipps72, Aubert73, Yu73, Garrett74, Hernandez75, Yuan75, Gorelic78, Glotz81, Schulze82, Karpel82, Kakegawa86, Abdukaiumov87, Teixido89, Kim91, Merryman99, Usary01, Murphy01, Jarry70, Pace71, Doctor72, Jarry73, Jarry73a, Fraser75, Yamamoto76, Muto77, Shen77, Vola77, Morgan78, Bailey79, Duester80, Sarmientos83, Brosius84, Liebke85, Steen86, Seol90, Albrechtsen91, Orosz91]

Map Position: [2,724,091 <- 2,724,210] (58.71 centisomes)
Length: 120 bp

Reactions known to consume the compound:

Not in pathways:
rRNA + S-adenosyl-L-methionine → rRNA containing N6,N6-dimethyladenine + S-adenosyl-L-homocysteine

Reactions known to produce the compound:

Not in pathways:
9S rRNA + 2 H2O → 5S rRNA + 2 a single-stranded RNA

tRNA processing :
a tRNA precursor with a 5' extension and a short 3' extension + H2O → a tRNA precursor with a short 3' extension + a single-stranded RNA
a tRNA precursor with a 5' extension + H2O → an uncharged tRNA + a single-stranded RNA


an mRNA + H2O → a single-stranded RNA + a single-stranded RNA
an mRNA + H2O → a single-stranded RNA + a single-stranded RNA
RNase E degradation substrate mRNA + n H2O → n a single-stranded RNA
YhaV endonuclease degradation substrate rRNA + H2O → 2 a single-stranded RNA
YhaV endonuclease degradation substrate mRNA + H2O → 2 a single-stranded RNA
RNase III mRNA processing substrate + 2 H2O → RNase III processing product mRNA + 2 a single-stranded RNA
23S rRNA[periplasmic space] + H2O[periplasmic space] → 2 a single-stranded RNA[periplasmic space]
an mRNA[periplasmic space] + H2O[periplasmic space] → 2 a single-stranded RNA[periplasmic space]
RNase G degradation substrate mRNA + H2O → 2 a single-stranded RNA
9S rRNA + 2 H2O → 5S rRNA + 2 a single-stranded RNA
RNase E mRNA processing substrate + n H2O → RNase E processing product mRNA + n a single-stranded RNA

Reactions known to both consume and produce the compound:

Not in pathways:
a single-stranded RNA + phosphate ↔ a single-stranded RNA + a nucleoside diphosphate

In Reactions of unknown directionality:

Not in pathways:
rRNA[periplasmic space] = 2 a single-stranded RNA[periplasmic space]


rRNA[periplasmic space] = 2 a single-stranded RNA[periplasmic space]

Genetic Regulation Schematic: ?

Unification Links: ASAP:ABE-0008519 , CGSC:205 , EchoBASE:EB4238 , EcoGene:EG30075 , EcoliWiki:b2588 , OU-Microarray:b2588 , PortEco:rrfG , RegulonDB:EG30075

GO Terms:

Biological Process: GO:0006412 - translation
Cellular Component: GO:0005737 - cytoplasm
GO:0022625 - cytosolic large ribosomal subunit

MultiFun Terms: cell structure ribosomes
information transfer protein related translation
information transfer RNA related rRNA, stable RNA


Gene Local Context (not to scale): ?

Transcription Units:

Notes:

History:
10/20/97 Gene b2588 from Blattner lab Genbank (v. M52) entry merged into EcoCyc gene EG30075.


References

Abdukaiumov87: Abdukaiumov M, Gimautdinova OI, Graifer DM, Zenkova MA, Karpova GG (1987). "[Preparation of Escherichia coli 70S ribosomes labeled with 35S]." Biokhimiia 52(9);1411-6. PMID: 3315008

Albrechtsen91: Albrechtsen B, Ross BM, Squires C, Squires CL (1991). "Transcriptional termination sequence at the end of the Escherichia coli ribosomal RNA G operon: complex terminators and antitermination." Nucleic Acids Res 19(8);1845-52. PMID: 1709493

Ammons01: Ammons D, Rampersad J (2001). "An E. coli 5S rRNA deletion mutant useful for the study of 5S rRNA structure/function relationships." Curr Microbiol 43(2);89-92. PMID: 11391469

Ammons99: Ammons D, Rampersad J, Fox GE (1999). "5S rRNA gene deletions cause an unexpectedly high fitness loss in Escherichia coli." Nucleic Acids Res 27(2);637-42. PMID: 9862991

Apirion78: Apirion D (1978). "Isolation, genetic mapping and some characterization of a mutation in Escherichia coli that affects the processing of ribonuleic acid." Genetics 90(4);659-71. PMID: 369943

Appel79: Appel B, Erdmann VA, Stulz J, Ackerman T (1979). "Determination of base pairing in Escherichia coli and Bacillus stearothermophilus 5S RNAs by infrared spectroscopy." Nucleic Acids Res 7(4);1043-57. PMID: 388350

Aubert68: Aubert M, Scott JF, Reynier M, Monier R (1968). "Rearrangement of the conformation of Escherichia coli 5S RNA." Proc Natl Acad Sci U S A 61(1);292-9. PMID: 4880610

Aubert73: Aubert M, Bellemare G, Monier R (1973). "Selective reaction of glyoxal with guanine residues in native and denatured Escherichia coli 5S RNA." Biochimie 55(2);135-42. PMID: 4198187

Azad79: Azad AA (1979). "Intermolecular base-paired interaction between complementary sequences present near the 3' ends of 5S rRNA and 18S (16S) rRNA might be involved in the reversible association of ribosomal subunits." Nucleic Acids Res 7(7);1913-29. PMID: 94160

Bailey79: Bailey SC, Apirion D (1979). "Repetitive DNA in Escherichia coli: multiple sequences complementary to small stable RNAs." Mol Gen Genet 172(3);339-43. PMID: 95791

Barciszewska96: Barciszewska MZ, Erdmann VA, Barciszewski J (1996). "Ribosomal 5S RNA: tertiary structure and interactions with proteins." Biol Rev Camb Philos Soc 71(1);1-25. PMID: 8603119

Barciszewska97: Barciszewska MZ (1997). "[RNA tectonics]." Postepy Biochem 43(4);267-74. PMID: 9572078

Bear77: Bear DG, Schleich T, Noller HF, Garrett RA (1977). "Alteration of 5S RNA conformation by ribosomal proteins L18 and L25." Nucleic Acids Res 4(7);2511-26. PMID: 333392

Bellemare72: Bellemare G, Jordan BR, Rocca-Serra J, Monier R (1972). "Accessibility of Escherichia coli 5S RNA base residues to chemical reagents. Influence of chemical alterations on the affinity of 5S RNA for the 50S subunit structure." Biochimie 54(11);1453-66. PMID: 4350484

Bellemare73: Bellemare G, Vigne R, Jordan BR (1973). "Interaction between Escherichia coli ribosomal proteins and 5S RNA molecules: recognition of prokaryotic 5S RNAs and rejection of eukaryotic 5S RNAs." Biochimie 55(1);29-35. PMID: 4578553

Berger75: Berger I, Geyl D, Bock A, Stoffler G, Wittmann HG (1975). "Localized mutagenesis of the aroE-strA section of the Escherichia coli chromosome coding for ribosomal proteins." Mol Gen Genet 141(3);207-11. PMID: 1107816

Bessarab98: Bessarab DA, Kaberdin VR, Wei CL, Liou GG, Lin-Chao S (1998). "RNA components of Escherichia coli degradosome: evidence for rRNA decay." Proc Natl Acad Sci U S A 95(6);3157-61. PMID: 9501232

Bitar75: Bitar KG, Wittmann-Liebold B (1975). "The primary structure of the 5s rRNA binding protein L25 of Escherichia coli ribosomes." Hoppe Seylers Z Physiol Chem 356(9);1343-52. PMID: 1100506

Boedtker67: Boedtker H, Kelling DG (1967). "The ordered structure of 5S RNA." Biochem Biophys Res Commun 29(5);758-66. PMID: 4865115

Bohm81: Bohm S, Fabian H, Welfle H (1981). "Universal secondary structures of prokaryotic and eukaryotic ribosomal 5S RNA derived from comparative analysis of their sequences." Acta Biol Med Ger 40(6);K19-24. PMID: 7034426

Brewer83: Brewer LA, Goelz S, Noller HF (1983). "Ribonucleic acid-protein cross-linking within the intact Escherichia coli ribosome, utilizing ethylene glycol bis[3-(2-ketobutyraldehyde) ether], a reversible, bifunctional reagent: synthesis and cross-linking within 30S and 50S subunits." Biochemistry 22(18);4303-9. PMID: 6354252

Brosius75: Brosius J, Schiltz E, Chen R (1975). "The primary structure of the 5S RNA binding protein L18 from Escherichia coli ribosomes." FEBS Lett 56(2);359-61. PMID: 1098937

Brosius84: Brosius J, Holy A (1984). "Regulation of ribosomal RNA promoters with a synthetic lac operator." Proc Natl Acad Sci U S A 81(22);6929-33. PMID: 6390428

Brownlee67: Brownlee GG, Sanger F, Barrell BG (1967). "Nucleotide sequence of 5S-ribosomal RNA from Escherichia coli." Nature 215(102);735-6. PMID: 4862513

Brunel91: Brunel C, Romby P, Westhof E, Ehresmann C, Ehresmann B (1991). "Three-dimensional model of Escherichia coli ribosomal 5 S RNA as deduced from structure probing in solution and computer modeling." J Mol Biol 221(1);293-308. PMID: 1717695

Burns80: Burns PD, Luoma GA, Marshall AG (1980). "Evaluation of base-pairing schemes for E. coli 5S RNA by 400 MHz proton nuclear magnetic resonance spectroscopy." Biochem Biophys Res Commun 96(2);805-11. PMID: 6158943

Cantor68: Cantor CR (1968). "The extent of base pairing in 5S ribosomal RNA." Proc Natl Acad Sci U S A 59(2);478-83. PMID: 4868898

Carpousis94: Carpousis AJ, Van Houwe G, Ehretsmann C, Krisch HM (1994). "Copurification of E. coli RNAase E and PNPase: evidence for a specific association between two enzymes important in RNA processing and degradation." Cell 76(5);889-900. PMID: 7510217

Chen78: Chen MC, Giege R, Lord RC, Rich A (1978). "Raman spectra of ten aqueous transfer RNAs and 5S RNA. Conformational comparison with yeast phenylalanine transfer RNA." Biochemistry 17(15);3134-8. PMID: 359039

Chiam83: Chiam CL, Wagner R (1983). "Composition of the Escherichia coli 70S ribosomal interface: a cross-linking study." Biochemistry 22(5);1193-200. PMID: 6340734

Christensen85: Christensen A, Mathiesen M, Peattie D, Garrett RA (1985). "Alternative conformers of 5S ribosomal RNA and their biological relevance." Biochemistry 24(9);2284-91. PMID: 2581611

Christiansen85: Christiansen J, Douthwaite SR, Christensen A, Garrett RA (1985). "Does unpaired adenosine-66 from helix II of Escherichia coli 5S RNA bind to protein L18?." EMBO J 4(4);1019-24. PMID: 2990903

Christiansen88: Christiansen J (1988). "The 9S RNA precursor of Escherichia coli 5S RNA has three structural domains: implications for processing." Nucleic Acids Res 16(15);7457-76. PMID: 3045757

Chu76: Chu FK, Maeba PY (1976). "Protein binding and subunit association activity in particles reconstituted from Escherichia coli MRE600 50S ribosomal components." Can J Biochem 54(5);470-6. PMID: 776368

Ciesiolka92: Ciesiolka J, Lorenz S, Erdmann VA (1992). "Structural analysis of three prokaryotic 5S rRNA species and selected 5S rRNA--ribosomal-protein complexes by means of Pb(II)-induced hydrolysis." Eur J Biochem 204(2);575-81. PMID: 1541273

Ciesiollka92: Ciesiollka J, Lorenz S, Erdmann VA (1992). "Different conformational forms of Escherichia coli and rat liver 5S rRNA revealed by Pb(II)-induced hydrolysis." Eur J Biochem 204(2);583-9. PMID: 1541274

Clark84: Clark MW, Lake JA (1984). "Unusual rRNA-linked complex of 50S ribosomal subunits isolated from an Escherichia coli RNase III mutant." J Bacteriol 157(3);971-4. PMID: 6199344

Cormack92: Cormack RS, Mackie GA (1992). "Structural requirements for the processing of Escherichia coli 5 S ribosomal RNA by RNase E in vitro." J Mol Biol 228(4);1078-90. PMID: 1474579

Cormack93: Cormack RS, Genereaux JL, Mackie GA (1993). "RNase E activity is conferred by a single polypeptide: overexpression, purification, and properties of the ams/rne/hmp1 gene product." Proc Natl Acad Sci U S A 90(19);9006-10. PMID: 8415644

Correll97: Correll CC, Freeborn B, Moore PB, Steitz TA (1997). "Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain." Cell 91(5);705-12. PMID: 9393863

Cramer68: Cramer F, Erdmann VA (1968). "Amount of adenine and uracil base pairs in E. coli 23S, 16S and 5S ribosomal RNA." Nature 217(136);92-3. PMID: 4868442

Dallas: Dallas A, Rycyna R, Moore P "A proposal for the conformation of loop E in Escherichia coli 5S rRNA." Biochem Cell Biol 73(11-12);887-97. PMID: 8722004

Dallas97: Dallas A, Moore PB (1997). "The loop E-loop D region of Escherichia coli 5S rRNA: the solution structure reveals an unusual loop that may be important for binding ribosomal proteins." Structure 5(12);1639-53. PMID: 9438864

Davis89: Davis DR, Yamaizumi Z, Nishimura S, Poulter CD (1989). "15N-labeled 5S RNA. Identification of uridine base pairs in Escherichia coli 5S RNA by 1H-15N multiple quantum NMR." Biochemistry 28(9);4105-8. PMID: 2752012

Delihas75: Delihas N, Dunn JJ, Erdmann VA (1975). "The reaction of 5S RNA in 70S ribosomes with kethoxal." FEBS Lett 58(1);76-80. PMID: 773691

Delihas82: Delihas N, Andersen J (1982). "Generalized structures of the 5S ribosomal RNAs." Nucleic Acids Res 10(22);7323-44. PMID: 7155895

Digweed81: Digweed M, Erdmann VA, Odom OW, Hardesty B (1981). "Fluorescence modification of Escherichia coli 5S RNA." Nucleic Acids Res 9(13);3187-98. PMID: 6169004

Doctor72: Doctor BP, Brenner DJ (1972). "Isolation of 5S ribonucleic acid cistrons and tRNA cistrons from Escherichia coli." Biochem Biophys Res Commun 46(2);449-56. PMID: 4550693

Dohme76: Dohme F, Nierhaus KH (1976). "Role of 5S RNA in assembly and function of the 50S subunit from Escherichia coli." Proc Natl Acad Sci U S A 73(7);2221-5. PMID: 781671

Dontsova90: Dontsova OA, Efimov AV, Kopylov AM (1990). "[The 5S rRNA-protein complex of Escherichia coli studied by carbodiimide modification]." Nauchnye Doki Vyss Shkoly Biol Nauki (2);22-30. PMID: 1693861

Dontsova94: Dontsova O, Tishkov V, Dokudovskaya S, Bogdanov A, Doring T, Rinke-Appel J, Thamm S, Greuer B, Brimacombe R (1994). "Stem-loop IV of 5S rRNA lies close to the peptidyltransferase center." Proc Natl Acad Sci U S A 91(10);4125-9. PMID: 7514294

Doolittle70: Doolittle WF, Pace NR (1970). "Synthesis of 5S ribosomal RNA in Escherichia coli after rifampicin treatment." Nature 228(267);125-9. PMID: 4918254

Douthwaite79: Douthwaite S, Garrett RA, Wagner R, Feunteun J (1979). "A ribonuclease-resistant region of 5S RNA and its relation to the RNA binding sites of proteins L18 and L25." Nucleic Acids Res 6(7);2453-70. PMID: 379819

Douthwaite81: Douthwaite S, Garrett RA (1981). "Secondary structure of prokaryotic 5S ribosomal ribonucleic acids: a study with ribonucleases." Biochemistry 20(25);7301-7. PMID: 6274397

Douthwaite82: Douthwaite S, Christensen A, Garrett RA (1982). "Binding site of ribosomal proteins on prokaryotic 5S ribonucleic acids: a study with ribonucleases." Biochemistry 21(10);2313-20. PMID: 6178424

Duester80: Duester GL, Holmes WM (1980). "The distal end of the ribosomal RNA operon rrnD of Escherichia coli contains a tRNA1thr gene, two 5s rRNA genes and a transcription terminator." Nucleic Acids Res 8(17);3793-807. PMID: 6255417

Egebjerg89: Egebjerg J, Christiansen J, Brown RS, Larsen N, Garrett RA (1989). "Protein L18 binds primarily at the junctions of helix II and internal loops A and B in Escherichia coli 5 S RNA. Implications for 5 S RNA structure." J Mol Biol 206(4);651-68. PMID: 2472486

Erdmann72: Erdmann VA, Doberer HG (1972). "Structure and function of 5S RNA: the role of the 3' terminus in 5S RNA function." Mol Gen Genet 114(2);89-94. PMID: 4553099

Erdmann73: Erdmann VA, Sprinzl M, Pongs O (1973). "The involvement of 5S RNA in the binding of tRNA to ribosomes." Biochem Biophys Res Commun 54(3);942-8. PMID: 4584885

Erdmann83: Erdmann VA, Digweed M, Pieler T (1983). "Dynamics of ribosomal RNA structure." J Biomol Struct Dyn 1(3);657-67. PMID: 6400893

Fanning81: Fanning TG, Traut RR (1981). "Topography of the E. coli 5S RNA-protein complex as determined by crosslinking with dimethyl suberimidate and dimethyl-3,3'-dithiobispropionimidate." Nucleic Acids Res 9(4);993-1004. PMID: 7015289

Feunteun70: Feunteun J, Jordan BR, Monier R (1970). "[Characterization of RNA 5S accumulated by a strain of Escherichia coli (RC relaxed) deficient in amino acids]." Bull Soc Chim Biol (Paris) 5(8);979-82. PMID: 4924729

Feunteun71: Feunteun J, Monier R (1971). "Accessibility of 5S RNA to ribonucleases in Escherichia coli ribosomes." Biochimie 53(5);657-60. PMID: 4941838

Forget70: Forget BG, Reynier M (1970). "Resistance of E. coli ribosomal 5S RNA to degradation by ribonuclease in reconstituted ribosomal particles." Biochem Biophys Res Commun 39(1);114-22. PMID: 4908845

Forget70a: Forget BG, Jordan B (1970). "5S RNA synthesized by Escherichia coli in presence of chloramphenicol: different 5'-terminal sequences." Science 167(917);382-4. PMID: 4902681

Fox75: Fox GW, Woese CR (1975). "5S RNA secondary structure." Nature 256(5517);505-7. PMID: 808733

Fox82: Fox JW, Wong KP (1982). "Acquisition of native conformation of ribosomal 5S ribonucleic acid from Escherichia coli. Hydrodynamic and spectroscopic studies on the unfolding and refolding of ribonucleic acid." Biochemistry 21(9);2096-102. PMID: 6807343

Fraser75: Fraser RS, Creanor J (1975). "The mechanism of inhibition of ribonucleic acid synthesis by 8-hydroxyquinoline and the antibiotic lomofungin." Biochem J 147(3);401-10. PMID: 810137

Galibert69: Galibert F, Sanfourche F (1969). "[Demonstration in sedimentation supernatant of ribosomes of a precursor 5S RNA pool]." C R Acad Sci Hebd Seances Acad Sci D 269(8);851-3. PMID: 4981108

Galibert71: Galibert F, Tiollais P, Sanfourche F, Boiron M (1971). "[Coordination of transcription of RNA 5 S and 23S and coordination of maturation of RNA 5S and of the ribosomal subunit 50S of Escherichia coli]." Eur J Biochem 20(3);381-91. PMID: 4931952

Garrett74: Garrett RA, Schulte C, Stoffler G, Gray P, Monier R (1974). "The release of proteins and 5S RNA during the unfolding of Escherichia coli ribosomes." FEBS Lett 49(1);1-4. PMID: 4216514

Garrett79: Garrett RA, Noller HF (1979). "Structures of complexes of 5S RNA with ribosomal proteins L5, L18 and L25 from Escherichia coli: identification of kethoxal-reactive sites on the 5S RNA." J Mol Biol 132(4);637-48. PMID: 393829

Georgellis92: Georgellis D, Arvidson S, von Gabain A (1992). "Decay of ompA mRNA and processing of 9S RNA are immediately affected by shifts in growth rate, but in opposite manners." J Bacteriol 174(16);5382-90. PMID: 1644765

Gewirth87: Gewirth DT, Abo SR, Leontis NB, Moore PB (1987). "Secondary structure of 5S RNA: NMR experiments on RNA molecules partially labeled with nitrogen-15." Biochemistry 26(16);5213-20. PMID: 2444255

Gewirth87a: Gewirth DT, Moore PB (1987). "Effects of mutation on the downfield proton nuclear magnetic resonance spectrum of the 5S RNA of Escherichia coli." Biochemistry 26(18);5657-65. PMID: 3314994

Gewirth88: Gewirth DT, Moore PB (1988). "Exploration of the L18 binding site on 5S RNA by deletion mutagenesis." Nucleic Acids Res 16(22);10717-32. PMID: 3060848

Ghora78: Ghora BK, Apirion D (1978). "Structural analysis and in vitro processing to p5 rRNA of a 9S RNA molecule isolated from an rne mutant of E. coli." Cell 15(3);1055-66. PMID: 365352

Ghora79: Ghora BK, Apirion D (1979). "5S ribosomal RNA is contained within a 25 S ribosomal RNA that accumulates in mutants of Escherichia coli defective in processing of ribosomal RNA." J Mol Biol 127(4);507-13. PMID: 372546

Glotz81: Glotz C, Zwieb C, Brimacombe R, Edwards K, Kossel H (1981). "Secondary structure of the large subunit ribosomal RNA from Escherichia coli, Zea mays chloroplast, and human and mouse mitochondrial ribosomes." Nucleic Acids Res 9(14);3287-306. PMID: 7024913

Goldblum81: Goldblum K, Apririon D (1981). "Inactivation of the ribonucleic acid-processing enzyme ribonuclease E blocks cell division." J Bacteriol 146(1);128-32. PMID: 6163761

Gorelic78: Gorelic L, Parker D (1978). "Studies of the effects of ultraviolet radiation on the structural integrities of ribosomal RNA components of the Escherichia coli 50S ribosomal subunit." Biochemistry 17(15);3152-62. PMID: 359042

Goringer84: Goringer HU, Szymkowiak C, Wagner R (1984). "Escherichia coli 5S RNA A and B conformers. Characterisation by enzymatic and chemical methods." Eur J Biochem 144(1);25-34. PMID: 6207022

Goringer84a: Goringer HU, Wagner R, Jacob WF, Dahlberg AE, Zwieb C (1984). "Oligonucleotide directed mutagenesis of Escherichia coli 5S ribosomal RNA: construction of mutant and structural analysis." Nucleic Acids Res 12(18);6935-50. PMID: 6091046

Goringer86: Goringer HU, Wagner R (1986). "Does 5S RNA from E. coli have a pseudoknotted structure?." Nucleic Acids Res 14(18);7473-85. PMID: 2429262

Goringer86a: Goringer HU, Wagner R (1986). "Construction and functional analysis of ribosomal 5S RNA from Escherichia coli with single base changes in the ribosomal protein binding sites." Biol Chem Hoppe Seyler 367(8);769-80. PMID: 2429677

Goringer88: Goringer HU, Wagner R (1988). "5S RNA structure and function." Methods Enzymol 164;721-47. PMID: 3071691

Gray72: Gray PN, Monier R (1972). "Partial localization of the 5S RNA binding site on 23S RNA." Biochimie 54(1);41-5. PMID: 4568456

Grune96: Grune M, Gorlach M, Soskic V, Klussmann S, Bald R, Furste JP, Erdmann VA, Brown LR (1996). "Initial analysis of 750 MHz NMR spectra of selective 15N-G,U labelled E. coli 5S rRNA." FEBS Lett 385(1-2);114-8. PMID: 8641454

Grune96a: Grune M, Furste JP, Klussmann S, Erdmann VA, Brown LR (1996). "Detection of multiple conformations of the E-domain of 5S rRNA from Escherichia coli in solution and in crystals by NMR spectroscopy." Nucleic Acids Res 24(13);2592-6. PMID: 8692701

Hancock82: Hancock J, Wagner R (1982). "A structural model of 5S RNA from E. coli based on intramolecular crosslinking evidence." Nucleic Acids Res 10(4);1257-69. PMID: 7041089

Hernandez75: Hernandez F, Vazquez D, Ballesta JP (1975). "Partial reconstitution of active ribosomes and 50S subunits." Biochemistry 14(7);1503. PMID: 164889

Herr75: Herr W, Noller HF (1975). "A fragment of 23S RNA containing a nucleotide sequence complementary to a region of 5S RNA." FEBS Lett 53(2);248-52. PMID: 1095416

Horne72: Horne JR, Erdmann VA (1972). "Isolation and characterization of 5S RNA-protein complexes from Bacillus stearothermophilus and Escherichia coli ribosomes." Mol Gen Genet 119(4);337-44. PMID: 4567807

Huber84: Huber PW, Wool IG (1984). "Nuclease protection analysis of ribonucleoprotein complexes: use of the cytotoxic ribonuclease alpha-sarcin to determine the binding sites for Escherichia coli ribosomal proteins L5, L18, and L25 on 5S rRNA." Proc Natl Acad Sci U S A 81(2);322-6. PMID: 6364140

Iwase99: Iwase R, Mahara A, Yamana K, Yamaoka T, Murakami A (1999). "Study on RNA structure by pyrene-labeled 2'-O-methyloligoribonucleotides." Nucleic Acids Symp Ser (42);115-6. PMID: 10780406

Jagadeeswaran80: Jagadeeswaran P, Cherayil JD (1980). "A general model for the conformational switch in 5S RNA during protein synthesis." J Theor Biol 83(2);369-75. PMID: 6157056

Jarry70: Jarry B, Rosset R (1970). "An attempt to localize 5S RNA cistrons in Escherichia coli." Biochem Biophys Res Commun 41(3);789-96. PMID: 4920877

Jarry71: Jarry B, Rosset R (1971). "Heterogeneity of 5S RNA in Escherichia coli." Mol Gen Genet 113(1);43-50. PMID: 4944480

Jarry73: Jarry B, Rosset R (1973). "Localization of some 5s RNA cistrons on Escherichia coli chromosome." Mol Gen Genet 121(2);151-62. PMID: 4571522

Jarry73a: Jarry B, Rosset R (1973). "Further mapping of 5S RNA cistrons in Escherichia coli." Mol Gen Genet 126(1);29-35. PMID: 4591367

Johnson91: Johnson KH, Gray DM (1991). "An estimate of the nearest neighbor base-pair content of 5S RNA using CD and absorption spectroscopy." Biopolymers 31(4);385-95. PMID: 1863690

Jordan69: Jordan B, Forget B (1969). "[Identification of the properties of a 5S RNA synthesized by E. coli in the presence of chloramphenicol]." Bull Soc Chim Biol (Paris) 51(10);1541. PMID: 4906608

Kaberdin00: Kaberdin VR, Walsh AP, Jakobsen T, McDowall KJ, von Gabain A (2000). "Enhanced cleavage of RNA mediated by an interaction between substrates and the arginine-rich domain of E. coli ribonuclease E." J Mol Biol 301(2);257-64. PMID: 10926508

Kaiser70: Kaiser II (1970). "Isolation of 5-fluorouracil-containing 5S ribonucleic acid from Escherichia coli." Biochemistry 9(3);569-73. PMID: 4906324

Kakegawa86: Kakegawa T, Hirose S, Kashiwagi K, Igarashi K (1986). "Effect of polyamines on in vitro reconstitution of ribosomal subunits." Eur J Biochem 158(2);265-9. PMID: 3089782

Kao80: Kao TH, Crothers DM (1980). "A proton-coupled conformational switch of Escherichia coli 5S ribosomal RNA." Proc Natl Acad Sci U S A 77(6);3360-4. PMID: 6158045

Karpel82: Karpel RL, Miller NS, Fresco JR (1982). "Mechanistic studies of ribonucleic acid renaturation by a helix-destabilizing protein." Biochemistry 21(9);2102-8. PMID: 6178431

Kim91: Kim J, Cheong C, Moore PB (1991). "Tetramerization of an RNA oligonucleotide containing a GGGG sequence." Nature 351(6324);331-2. PMID: 1709723

Kime82: Kime MJ, Moore PB (1982). "NMR evidence for the existence of two native conformations of 5S RNA." Nucleic Acids Res 10(16);4973-83. PMID: 6182528

Kime83: Kime MJ, Moore PB (1983). "Nuclear Overhauser experiments at 500 MHz on the downfield proton spectrum of a ribonuclease-resistant fragment of 5S ribonucleic acid." Biochemistry 22(11);2615-22. PMID: 6347249

Kime83a: Kime MJ, Moore PB (1983). "Nuclear Overhauser experiments at 500 MHz on the downfield proton spectra of 5S ribonucleic acid and its complex with ribosomal protein L25." Biochemistry 22(11);2622-9. PMID: 6347250

Kime84: Kime MJ, Gewirth DT, Moore PB (1984). "Assignment of resonances in the downfield proton spectrum of Escherichia coli 5S RNA and its nucleoprotein complexes using components of a ribonuclease-resistant fragment." Biochemistry 23(15);3559-68. PMID: 6380589

Kime84a: Kime MJ, Moore PB (1984). "Escherichia coli ribosomal 5S RNA-protein L25 nucleoprotein complex: effects of RNA binding on the protein structure and the nature of the interaction." Biochemistry 23(8);1688-95. PMID: 6372859

Lee02: Lee K, Bernstein JA, Cohen SN (2002). "RNase G complementation of rne null mutation identifies functional interrelationships with RNase E in Escherichia coli." Mol Microbiol 43(6);1445-56. PMID: 11952897

Leontis84: Leontis NB, Moore PB (1984). "A small angle x-ray scattering study of a fragment derived from E. coli 5S RNA." Nucleic Acids Res 12(4);2193-203. PMID: 6366745

Leontis86: Leontis NB, Moore PB (1986). "NMR evidence for dynamic secondary structure in helices II and III of the RNA of Escherichia coli." Biochemistry 25(13);3916-25. PMID: 2427108

Leontis86a: Leontis NB, Moore PB (1986). "Imino proton exchange in the 5S RNA of Escherichia coli and its complex with protein L25 at 490 MHz." Biochemistry 25(19);5736-44. PMID: 3535886

Leontis86b: Leontis NB, Ghosh P, Moore PB (1986). "Effect of magnesium ion on the structure of the 5S RNA from Escherichia coli. An imino proton magnetic resonance study of the helix I, IV, and V regions of the molecule." Biochemistry 25(23);7386-92. PMID: 3542026

Leontis98: Leontis NB, Westhof E (1998). "The 5S rRNA loop E: chemical probing and phylogenetic data versus crystal structure." RNA 4(9);1134-53. PMID: 9740131

Lewis70: Lewis JB, Doty P (1970). "Derivation of the secondary structure of 5S RNA from its binding of complementary oligonucleotides." Nature 225(232);510-2. PMID: 4904262

Lewis77: Lewis JB, Doty P (1977). "Identification of the single-strand regions in Escherichia coli 5S RNA, native and A forms, by the binding of oligonucleotides." Biochemistry 16(23);5016-25. PMID: 334253

Li95: Li Z, Deutscher MP (1995). "The tRNA processing enzyme RNase T is essential for maturation of 5S RNA." Proc Natl Acad Sci U S A 92(15);6883-6. PMID: 7542780

Liebke85: Liebke H, Hatfull G (1985). "The sequence of the distal end of the E. coli ribosomal RNA rrnE operon indicates conserved features are shared by rrn operons." Nucleic Acids Res 13(15);5515-25. PMID: 2412207

Lind: Lind AIa, Villems RL, Uuskiula LS "[5S RNA: structure and function]." Usp Sovrem Biol 86(1);3-18. PMID: 152015

Lorenz: Lorenz S, Hartmann RK, Schultze S, Ulbrich N, Erdmann VA "Structural analysis of prokaryotic and eukaryotic 5S rRNAs by RNase H." Biochimie 71(11-12);1185-91. PMID: 2561346

Lorenz87: Lorenz S, Hartmann RK, Piel N, Ulbrich N, Erdmann VA (1987). "Structural analysis of 5S rRNA, 5S rRNA-protein complexes and ribosomes employing RNase H and d(GTTCGG)." Eur J Biochem 163(2);239-46. PMID: 2434327

Lu00: Lu M, Steitz TA (2000). "Structure of Escherichia coli ribosomal protein L25 complexed with a 5S rRNA fragment at 1.8-A resolution." Proc Natl Acad Sci U S A 97(5);2023-8. PMID: 10696113

Lund77: Lund E, Dahlberg JE (1977). "Spacer transfer RNAs in ribosomal RNA transcripts of E. coli: processing of 30S ribosomal RNA in vitro." Cell 11(2);247-62. PMID: 329997

Luoma78: Luoma GA, Marshall AG (1978). "Laser Raman evidence for new cloverleaf secondary structures for eukaryotic 5.8S RNA and prokaryotic 5S RNA." Proc Natl Acad Sci U S A 75(10);4901-5. PMID: 368804

Luoma82: Luoma GA, Herring FG, Marshall AG (1982). "Flexibility of end-labeled polymers from electron spin resonance line-shape analysis: 3' terminus of transfer ribonucleic acid and 5S ribonucleic acid." Biochemistry 21(25);6591-8. PMID: 6295470

Mahara00: Mahara A, Iwase R, Yamana K, Yamaoka T, Murakami A (2000). "Characterization of RNA structure by bis-pyrene-labeled 2'-O-methyloligonucleotides." Nucleic Acids Symp Ser (44);199-200. PMID: 12903337

Maimets: Maimets TO, Ustav MB, Villems RL, Saarma MIu, Lind AIa "[Binding of Escherichia coli 50S ribosomal subunit proteins with two large 5S RNA fragments]." Mol Biol (Mosk) 15(3);569-74. PMID: 7019670

Marshall77: Marshall AG, Smith JL (1977). "Nuclear-spin-labeled nucleic acids. 1 19F nuclear magnetic resonance of Escherchia coli 5-fluorouracil-5S-RNA." J Am Chem Soc 99(2);635-6. PMID: 318664

Marshall80: Marshall AG, Smith JL (1980). "Raman and 19F(1H) nuclear Overhauser evidence for a rigid solution conformation of Escherichia coli 5-fluorouracil 5S ribonucleic acid." Biochemistry 19(26);5955-9. PMID: 6162474

Matveev: Matveev SV, Filimonov VV, Privalov PL "[A thermodynamic approach to the study of the structural organization of 5S RNA from Escherichia coli ribosomes. 1. Analysis of scanned microcalorimetry data]." Mol Biol (Mosk) 16(6);1234-44. PMID: 6759922

Matveeva: Matveev SV, Filimonov VV, Privalov PL "[Thermodynamic approach to the study of the structural organization of 5S from Escherichia coli ribosomes. II. Analysis of optical, curved melting]." Mol Biol (Mosk) 17(1);172-80. PMID: 6346054

Melefors91: Melefors O, von Gabain A (1991). "Genetic studies of cleavage-initiated mRNA decay and processing of ribosomal 9S RNA show that the Escherichia coli ams and rne loci are the same." Mol Microbiol 5(4);857-64. PMID: 1713283

Merryman99: Merryman C, Moazed D, Daubresse G, Noller HF (1999). "Nucleotides in 23S rRNA protected by the association of 30S and 50S ribosomal subunits." J Mol Biol 285(1);107-13. PMID: 9878392

Metelev90: Metelev VG, Krynetskaia NF, Purmal' AA, Shabarova ZA (1990). "[Hybridase cleavage of RNA. I. Oligonucleotide probes for regiospecific RNA cleavage]." Bioorg Khim 16(4);507-13. PMID: 1695848

Monier68: Monier R (1968). "[The structure of ribosomes and 5S RNA]." Bull Soc Chim Biol (Paris) 50(12);2277-90. PMID: 4890842

Moore83: Moore PB, Kime MJ, Leontis NB, Abdel-Meguid SS (1983). "Physical studies on a nucleoprotein from the ribosome of E. coli." J Biomol Struct Dyn 1(2);383-94. PMID: 6401116

Moore88: Moore PB, Abo S, Freeborn B, Gewirth DT, Leontis NB, Sun G (1988). "Preparation of 5S RNA-related materials for nuclear magnetic resonance and crystallography studies." Methods Enzymol 164;158-74. PMID: 3071660

Morell68: Morell P, Marmur J (1968). "Association of 5S ribonucleic acid to 50S ribosomal subunits of Escherichia coli and Bacillus subtilis." Biochemistry 7(3);1141-52. PMID: 4968699

Morgan78: Morgan EA, Ikemura T, Lindahl L, Fallon AM, Nomura M (1978). "Some rRNA operons in E. coli have tRNA genes at their distal ends." Cell 13(2);335-44. PMID: 342117

Mueller00: Mueller F, Sommer I, Baranov P, Matadeen R, Stoldt M, Wohnert J, Gorlach M, van Heel M, Brimacombe R (2000). "The 3D arrangement of the 23 S and 5 S rRNA in the Escherichia coli 50 S ribosomal subunit based on a cryo-electron microscopic reconstruction at 7.5 A resolution." J Mol Biol 298(1);35-59. PMID: 10756104

Muller86: Muller JJ, Zalkova TN, Zirwer D, Misselwitz R, Gast K, Serdyuk IN, Welfle H, Damaschun G (1986). "Comparison of the structure of ribosomal 5S RNA from E. coli and from rat liver using X-ray scattering and dynamic light scattering." Eur Biophys J 13(5);301-7. PMID: 3525135

Murphy01: Murphy JC, Fox GE, Willson RC (2001). "RNA isolation and fractionation with compaction agents." Anal Biochem 295(2);143-8. PMID: 11488615

Muto77: Muto A (1977). "Control of ribosomal RNA synthesis in Escherichia coli. II. Ribosomal RNA synthesis in isolated nucleoids." Mol Gen Genet 152(3);153-9. PMID: 327272

Nagano88: Nagano K, Harel M, Takezawa M (1988). "Prediction of three-dimensional structure of Escherichia coli ribosomal RNA." J Theor Biol 134(2);199-256. PMID: 2468977

Nazar83: Nazar RN, Wildeman AG (1983). "Three helical domains form a protein binding site in the 5S RNA-protein complex from eukaryotic ribosomes." Nucleic Acids Res 11(10);3155-68. PMID: 6344007

Nazar91: Nazar RN (1991). "Higher order structure of the ribosomal 5 S RNA." J Biol Chem 266(7);4562-7. PMID: 1705555

Neidhardt87: Neidhardt FC, Ingraham J, Low KB, Magasanik B, Schaechter M, Umbarger HE "Escherichia coli and Salmonella typhimurium, Cellular and Molecular Biology, Volumes 1 & 2." Microbiology, Washington, D.C., 1987.

Neidhardt96: Neidhardt FC, Curtiss III R, Ingraham JL, Lin ECC, Low Jr KB, Magasanik B, Reznikoff WS, Riley M, Schaechter M, Umbarger HE "Escherichia coli and Salmonella, Cellular and Molecular Biology, Second Edition." American Society for Microbiology, Washington, D.C., 1996.

Newberry78: Newberry V, Brosius J, Garrett R (1978). "Fragment of protein L18 from the Escherichia coli ribosome that contains the 5S RNA binding site." Nucleic Acids Res 5(6);1753-66. PMID: 353728

Newberry80: Newberry V, Garrett RA (1980). "The role of the basic N-terminal region of protein L18 in 5S RNA-23S RNA complex formation." Nucleic Acids Res 8(18);4131-42. PMID: 6159586

Nowotny88: Nowotny P, Nowotny V, Voss H, Nierhaus KH (1988). "Preparation and activity measurements of deuterated 50S subunits for neutron-scattering analysis." Methods Enzymol 164;131-47. PMID: 3071658

Odom80: Odom OW, Robbins DJ, Lynch J, Dottavio-Martin D, Kramer G, Hardesty B (1980). "Distances between 3' ends of ribosomal ribonucleic acids reassembled into Escherichia coli ribosomes." Biochemistry 19(26);5947-54. PMID: 6162473

Okada00: Okada S, Okada T, Aimi T, Morinaga T, Itoh T (2000). "HSP70 and ribosomal protein L2: novel 5S rRNA binding proteins in Escherichia coli." FEBS Lett 485(2-3);153-6. PMID: 11094158

Orosz91: Orosz A, Boros I, Venetianer P (1991). "Analysis of the complex transcription termination region of the Escherichia coli rrnB gene." Eur J Biochem 201(3);653-9. PMID: 1718749

Osswald90: Osswald M, Greuer B, Brimacombe R (1990). "Localization of a series of RNA-protein cross-link sites in the 23S and 5S ribosomal RNA from Escherichia coli, induced by treatment of 50S subunits with three different bifunctional reagents." Nucleic Acids Res 18(23);6755-60. PMID: 1702198

Osswald99: Osswald M, Brimacombe R (1999). "The environment of 5S rRNA in the ribosome: cross-links to 23S rRNA from sites within helices II and III of the 5S molecule." Nucleic Acids Res 27(11);2283-90. PMID: 10325415

Osterberg76: Osterberg R, Sjoberg B (1976). "Small-angle x-ray scattering study of the 5S RNA binding proteins L18 and L25 from Escherichia coli ribosomes." FEBS Lett 65(1);73-6. PMID: 776688

Ostergaard98: Ostergaard P, Phan H, Johansen LB, Egebjerg J, Ostergaard L, Porse BT, Garrett RA (1998). "Assembly of proteins and 5 S rRNA to transcripts of the major structural domains of 23 S rRNA." J Mol Biol 284(2);227-40. PMID: 9813114

Pace71: Pace B, Pace NR (1971). "Gene dosage for 5S ribosomal ribonucleic acid in Escherichia coli ad Bacillus megaterium." J Bacteriol 105(1);142-9. PMID: 4993318

Pace82: Pace B, Matthews EA, Johnson KD, Cantor CR, Pace NR (1982). "Conserved 5S rRNA complement to tRNA is not required for protein synthesis." Proc Natl Acad Sci U S A 79(1);36-40. PMID: 6798570

Parker83: Parker KK, Wickstrom E (1983). "Crosslinking of Escherichia coli 50S ribosomal subunits with chlorambucilyl oligoprolyl phenylalanyl-tRNA molecular rulers." Nucleic Acids Res 11(2);515-24. PMID: 6338479

Peattie81: Peattie DA, Douthwaite S, Garrett RA, Noller HF (1981). "A "bulged" double helix in a RNA-protein contact site." Proc Natl Acad Sci U S A 78(12);7331-5. PMID: 7038676

Perederina02: Perederina A, Nevskaya N, Nikonov O, Nikulin A, Dumas P, Yao M, Tanaka I, Garber M, Gongadze G, Nikonov S (2002). "Detailed analysis of RNA-protein interactions within the bacterial ribosomal protein L5/5S rRNA complex." RNA 8(12);1548-57. PMID: 12515387

Philipps72: Philipps GR, Timko JL (1972). "Simple method for the characterization of 5S RNA." Anal Biochem 45(1);319-25. PMID: 4621557

Pieler82: Pieler T, Erdmann VA (1982). "Three-dimensional structural model of eubacterial 5S RNA that has functional implications." Proc Natl Acad Sci U S A 79(15);4599-603. PMID: 6181508

Pieler84: Pieler T, Schreiber A, Erdmann VA (1984). "Comparative structural analysis of eubacterial 5S rRNA by oxidation of adenines in the N-1 position." Nucleic Acids Res 12(7);3115-26. PMID: 6201825

Pieler85: Pieler T, Digweed M, Erdmann VA (1985). "RNA structural dynamics: pre-melting and melting transitions in E. coli 5S rRNA." J Biomol Struct Dyn 3(3);495-514. PMID: 3917034

Raacke68: Raacke ID (1968). ""Cloverleaf" conformation for 5S RNAs." Biochem Biophys Res Commun 31(4);528-33. PMID: 4872142

Rabin79: Rabin D, Crothers DM (1979). "Analysis of RNA secondary structure by photochemical reversal of psoralen crosslinks." Nucleic Acids Res 7(3);689-703. PMID: 116192

Ramstein81: Ramstein J, Erdmann VA (1981). "A hydrogen exchange study of Escherichia coli 5S RNA." Nucleic Acids Res 9(16);4081-6. PMID: 6170933

Reynier69: Reynier M, Monier R (1969). "[Escherichia coli ribosomes. 3. Study of reversible dissociation of 5S RNA by lithium chloride]." Bull Soc Chim Biol (Paris) 50(10);1583-600. PMID: 4895025

Richards69: Richards EG (1969). "5S RNA. An analysis of possible base pairing schemes." Eur J Biochem 10(1);36-42. PMID: 4899461

Richards72: Richards EG, Geroch ME, Simpkins H, Lecanidou R (1972). "Optical properties and base pairing of E. coli 5S RNA." Biopolymers 11(5);1031-9. PMID: 4556238

Robins68: Robins HI, Raacke ID (1968). "A simplified procedure for the simultaneous isolation of 4S and 5S RNA." Biochem Biophys Res Commun 33(2);240-6. PMID: 4881049

Rohl82: Rohl R, Roth HE, Nierhaus KH (1982). "Inter-protein dependences during assembly of the 50S subunit from Escherichia coli ribosomes." Hoppe Seylers Z Physiol Chem 363(2);143-57. PMID: 6174405

Rohl82a: Rohl R, Nierhaus KH (1982). "Assembly map of the large subunit (50S) of Escherichia coli ribosomes." Proc Natl Acad Sci U S A 79(3);729-33. PMID: 7038683

Sarmientos83: Sarmientos P, Sylvester JE, Contente S, Cashel M (1983). "Differential stringent control of the tandem E. coli ribosomal RNA promoters from the rrnA operon expressed in vivo in multicopy plasmids." Cell 32(4);1337-46. PMID: 6188537

Schneider03a: Schneider DA, Ross W, Gourse RL (2003). "Control of rRNA expression in Escherichia coli." Curr Opin Microbiol 6(2);151-6. PMID: 12732305

Schreiber79: Schreiber JP, Hsiung N, Cantor CR (1979). "Fluorescence studies of the accessibility of the 3' ends of the ribosomal RNAs in Escherichia coli ribosomes and subunits." Nucleic Acids Res 6(1);181-93. PMID: 370785

Schulte75: Schulte C, Schiltz E, Garrent R (1975). "The characterisation of a fragment of ribosomal protein S4 that is protected against trypsin digestion by 16S ribosomal RNA of Escherichia coli." Nucleic Acids Res 2(6);931-41. PMID: 1096086

Schulze82: Schulze H, Nierhaus KH (1982). "Minimal set of ribosomal components for reconstitution of the peptidyltransferase activity." EMBO J 1(5);609-13. PMID: 6765232

Scott68: Scott JF, Monier R, Aubert M, Reynier M (1968). "Some optical properties of 5S-RNA from E. coli." Biochem Biophys Res Commun 33(5);794-800. PMID: 4881332

Seol90: Seol W, Shatkin AJ (1990). "Sequence of the distal end of E. coli ribosomal RNA rrnG operon." Nucleic Acids Res 18(10);3056. PMID: 2190187

Sergiev00: Sergiev PV, Bogdanov AA, Dahlberg AE, Dontsova O (2000). "Mutations at position A960 of E. coli 23 S ribosomal RNA influence the structure of 5 S ribosomal RNA and the peptidyltransferase region of 23 S ribosomal RNA." J Mol Biol 299(2);379-89. PMID: 10860746

Sergiev98: Sergiev P, Dokudovskaya S, Romanova E, Topin A, Bogdanov A, Brimacombe R, Dontsova O (1998). "The environment of 5S rRNA in the ribosome: cross-links to the GTPase-associated area of 23S rRNA." Nucleic Acids Res 26(11);2519-25. PMID: 9592132

Shen77: Shen V, Bremer H (1977). "Rate of ribosomal ribonucleic acid chain elongation in Escherichia coli B/r during chloramphenicol treatment." J Bacteriol 130(3);1109-16. PMID: 324975

Shpanchenko96: Shpanchenko OV, Zvereva MI, Dontsova OA, Nierhaus KH, Bogdanov AA (1996). "5S rRNA sugar-phosphate backbone protection in complexes with specific ribosomal proteins." FEBS Lett 394(1);71-5. PMID: 8925931

Shpanchenko98: Shpanchenko OV, Dontsova OA, Bogdanov AA, Nierhaus KH (1998). "Structure of 5S rRNA within the Escherichia coli ribosome: iodine-induced cleavage patterns of phosphorothioate derivatives." RNA 4(9);1154-64. PMID: 9740132

Siddiqui68: Siddiqui MA, Hosokawa K (1968). "Role of 5S ribosomal RNA in polypeptide synthesis. II. Dissociation of 5S ribosomal RNA from 50S ribosomes in Escherichia coli." Biochem Biophys Res Commun 32(1);1-8. PMID: 4874775

Siddiqui69: Siddiqui MA, Hosokawa K (1969). "Role of 5S ribosomal RNA in polypeptide synthesis." Biochem Biophys Res Commun 36(5);711-20. PMID: 4980101

Silberklang83: Silberklang M, RajBhandary UL, Luck A, Erdmann VA (1983). "Chemical reactivity of E. coli 5S RNA in situ in the 50S ribosomal subunit." Nucleic Acids Res 11(3);605-17. PMID: 6340064

Speek82: Speek M, Lind A (1982). "Structural analyses of E. coli 5S RNA fragments, their associates and complexes with proteins L18 and L25." Nucleic Acids Res 10(3);947-63. PMID: 6278442

Spierer78: Spierer P, Zimmermann RA (1978). "Stoichiometry, cooperativity, and stability of interactions between 5S RNA and proteins L5, L18, and L25 from the 50S ribosomal subunit of Escherichia coli." Biochemistry 17(13);2474-9. PMID: 354687

Spierer78a: Spierer P, Bogdanov AA, Zimmermann RA (1978). "Parameters for the interaction of ribosomal proteins L5, L18, and L25 with 5S RNA from Escherichia coli." Biochemistry 17(25);5394-8. PMID: 365228

Spierer79: Spierer P, Wang CC, Marsh TL, Zimmermann RA (1979). "Cooperative interactions among protein and RNA components of the 50S ribosomal subunit of Escherichia coli." Nucleic Acids Res 6(4);1669-82. PMID: 109811

Srivastava91: Srivastava AK, Schlessinger D (1991). "Structure and organization of ribosomal DNA." Biochimie 73(6);631-8. PMID: 1764510

Steen86: Steen R, Dahlberg AE, Lade BN, Studier FW, Dunn JJ (1986). "T7 RNA polymerase directed expression of the Escherichia coli rrnB operon." EMBO J 5(5);1099-103. PMID: 3013618

Stiege82: Stiege W, Zwieb C, Brimacombe R (1982). "Precise localisation of three intra-RNA cross-links in 23S RNA and one in 5S RNA, induced by treatment of Escherichia coli 50S ribosomal subunits with bis-(2-chloroethyl)-methylamine." Nucleic Acids Res 10(22);7211-29. PMID: 6818528

StofflerMeilick81: Stoffler-Meilicke M, Stoffler G, Odom OW, Zinn A, Kramer G, Hardesty B (1981). "Localization of 3' ends of 5S and 23S rRNAs in reconstituted subunits of Escherichia coli ribosomes." Proc Natl Acad Sci U S A 78(9);5538-42. PMID: 7029538

Stoldt99: Stoldt M, Wohnert J, Ohlenschlager O, Gorlach M, Brown LR (1999). "The NMR structure of the 5S rRNA E-domain-protein L25 complex shows preformed and induced recognition." EMBO J 18(22);6508-21. PMID: 10562563

Szeberenyi84: Szeberenyi J, Roy MK, Vaidya HC, Apirion D (1984). "7S RNA, containing 5S ribosomal RNA and the termination stem, is a specific substrate for the two RNA processing enzymes RNase III and RNase E." Biochemistry 23(13);2952-7. PMID: 6380579

Szymkowiak85: Szymkowiak C, Wagner R (1985). "Analysis of a sequence region of 5S RNA from E. coli cross-linked in situ to the ribosomal protein L25." Nucleic Acids Res 13(11);3953-68. PMID: 3892485

Tanaka85: Tanaka T, Ogata K (1985). "[The structure and the evolution of the 5S RNA protein complex]." Seikagaku 57(11);1531-4. PMID: 3913708

Teixido89: Teixido J, Altamura S, Londei P, Amils R (1989). "Structural and functional exchangeability of 5 S RNA species from the eubacterium E.coli and the thermoacidophilic archaebacterium Sulfolobus solfataricus." Nucleic Acids Res 17(3);845-51. PMID: 2493632

Tewari83: Tewari DS, Burma DP (1983). "Incorporation of 5S RNA into 16S-23S RNA complex." Biochem Biophys Res Commun 114(1);348-54. PMID: 6349628

Usary01: Usary J, Champney WS (2001). "Erythromycin inhibition of 50S ribosomal subunit formation in Escherichia coli cells." Mol Microbiol 40(4);951-62. PMID: 11401702

Vester88: Vester B, Egebjerg J, Garrett R, Christiansen J (1988). "Primer-directed deletions in 5S ribosomal RNA." Methods Enzymol 164;710-21. PMID: 3071690

Vigne71: Vigne R, Jordan BR (1971). "Conformational analysis of RNA molecules by partial RNAse digestion and two dimensional acrylamide gel electrophoresis. Application to E. coli 5S RNA." Biochimie 53(9);981-6. PMID: 4948666

Vigne77: Vigne R, Jordan BR (1977). "Partial enzyme digestion studies on Escherichia coli, Pseudomonas, Chlorella, Drosophila, HeLa and yeast 5S RNAs support a general class of 5S RNA models." J Mol Evol 10(1);77-86. PMID: 409850

Vola77: Vola C, Jarry B, Rosset R (1977). "Linkage of 5S RNA and 16S+23S RNA genes on the E. coli chromosome." Mol Gen Genet 153(3);337-41. PMID: 331075

Wagner78: Wagner R, Garrett RA (1978). "A new RNA-RNA crosslinking reagent and its application to ribosomal 5S RNA." Nucleic Acids Res 5(11);4065-75. PMID: 724507

Weidner77: Weidner H, Crothers DM (1977). "Pathway-dependent refolding of E. coli 5S RNA." Nucleic Acids Res 4(10);3401-14. PMID: 337236

White92: White SA, Nilges M, Huang A, Brunger AT, Moore PB (1992). "NMR analysis of helix I from the 5S RNA of Escherichia coli." Biochemistry 31(6);1610-21. PMID: 1371071

Wohnert99: Wohnert J, Dingley AJ, Stoldt M, Gorlach M, Grzesiek S, Brown LR (1999). "Direct identification of NH...N hydrogen bonds in non-canonical base pairs of RNA by NMR spectroscopy." Nucleic Acids Res 27(15);3104-10. PMID: 10454606

Yamamoto76: Yamamoto M, Lindahl L, Nomura M (1976). "Synthesis of ribosomal RNA in E. coli: analysis using deletion mutants of a lambda transducing phage carrying ribosomal RNA genes." Cell 7(2);179-90. PMID: 782717

Yu73: Yu RS (1973). "A simple method for the preparation of 5S RNA from Escherichia coli." Hoppe Seylers Z Physiol Chem 354(2);125-30. PMID: 4609878

Yuan75: Yuan D, Shen V (1975). "Stability of ribosomal and transfer ribonucleic acid in Escherichia coli B/r after treatment with ethylenedinitrilotetraacetic acid and rifampicin." J Bacteriol 122(2);425-32. PMID: 805122

Zhang89: Zhang P, Moore PB (1989). "An NMR study of the helix V-loop E region of the 5S RNA from Escherichia coli." Biochemistry 28(11);4607-15. PMID: 2669961

Zhang89a: Zhang P, Rycyna R, Moore PB (1989). "A study of the conformation of 5S RNA by 31P NMR." Nucleic Acids Res 17(18);7295-302. PMID: 2677996

Zhang89b: Zhang P, Popieniek P, Moore PB (1989). "Physical studies of 5S RNA variants at position 66." Nucleic Acids Res 17(21);8645-56. PMID: 2479908

Zhong94: Zhong M, Kallenbach NR (1994). "Mapping tRNA and 5S RNA tertiary structures by charge dependent Fe(II)-catalyzed cleavage." J Biomol Struct Dyn 11(4);901-11. PMID: 7515624

Zimmermann78: Zimmermann J, Erdmann VA (1978). "Identification of Escherichia coli and Bacillus stearothermophilus ribosomal protein binding sites on Escherichia coli 5S RNA." Mol Gen Genet 160(3);247-57. PMID: 353489

Zuo02: Zuo Y, Deutscher MP (2002). "The physiological role of RNase T can be explained by its unusual substrate specificity." J Biol Chem 277(33);29654-61. PMID: 12050169

Zvereva98: Zvereva MI, Shpanchenko OV, Dontsova OA, Nierhaus KH, Bogdanov AA (1998). "Effect of point mutations at position 89 of the E. coli 5S rRNA on the assembly and activity of the large ribosomal subunit." FEBS Lett 421(3);249-51. PMID: 9468316

Other References Related to Gene Regulation

Afflerbach98: Afflerbach H, Schroder O, Wagner R (1998). "Effects of the Escherichia coli DNA-binding protein H-NS on rRNA synthesis in vivo." Mol Microbiol 28(3);641-53. PMID: 9632265

Artsimovitch04: Artsimovitch I, Patlan V, Sekine S, Vassylyeva MN, Hosaka T, Ochi K, Yokoyama S, Vassylyev DG (2004). "Structural basis for transcription regulation by alarmone ppGpp." Cell 117(3);299-310. PMID: 15109491

Condon95: Condon C, Squires C, Squires CL (1995). "Control of rRNA transcription in Escherichia coli." Microbiol Rev 59(4);623-45. PMID: 8531889

Dennis04: Dennis PP, Ehrenberg M, Bremer H (2004). "Control of rRNA synthesis in Escherichia coli: a systems biology approach." Microbiol Mol Biol Rev 68(4);639-68. PMID: 15590778

Gralla05: Gralla JD (2005). "Escherichia coli ribosomal RNA transcription: regulatory roles for ppGpp, NTPs, architectural proteins and a polymerase-binding protein." Mol Microbiol 55(4);973-7. PMID: 15686546

Hillebrand05: Hillebrand A, Wurm R, Menzel A, Wagner R (2005). "The seven E. coli ribosomal RNA operon upstream regulatory regions differ in structure and transcription factor binding efficiencies." Biol Chem 386(6);523-34. PMID: 16006239

Hirvonen01: Hirvonen CA, Ross W, Wozniak CE, Marasco E, Anthony JR, Aiyar SE, Newburn VH, Gourse RL (2001). "Contributions of UP elements and the transcription factor FIS to expression from the seven rrn P1 promoters in Escherichia coli." J Bacteriol 183(21);6305-14. PMID: 11591675

Lemke11: Lemke JJ, Sanchez-Vazquez P, Burgos HL, Hedberg G, Ross W, Gourse RL (2011). "Direct regulation of Escherichia coli ribosomal protein promoters by the transcription factors ppGpp and DksA." Proc Natl Acad Sci U S A 108(14);5712-7. PMID: 21402902

Lindahl86: Lindahl L, Zengel JM (1986). "Ribosomal genes in Escherichia coli." Annu Rev Genet 20;297-326. PMID: 2434021

Newlands93: Newlands JT, Gaal T, Mecsas J, Gourse RL (1993). "Transcription of the Escherichia coli rrnB P1 promoter by the heat shock RNA polymerase (E sigma 32) in vitro." J Bacteriol 175(3);661-8. PMID: 8423142

Paul04: Paul BJ, Barker MM, Ross W, Schneider DA, Webb C, Foster JW, Gourse RL (2004). "DksA: a critical component of the transcription initiation machinery that potentiates the regulation of rRNA promoters by ppGpp and the initiating NTP." Cell 118(3);311-22. PMID: 15294157

Paul04a: Paul BJ, Ross W, Gaal T, Gourse RL (2004). "rRNA Transcription in Escherichia coli." Annu Rev Genet 38:749-70. PMID: 15568992

Pul05: Pul U, Wurm R, Lux B, Meltzer M, Menzel A, Wagner R (2005). "LRP and H-NS--cooperative partners for transcription regulation at Escherichia coli rRNA promoters." Mol Microbiol 58(3);864-76. PMID: 16238633

Schneider03b: Schneider DA, Gourse RL (2003). "Changes in Escherichia coli rRNA promoter activity correlate with changes in initiating nucleoside triphosphate and guanosine 5' diphosphate 3'-diphosphate concentrations after induction of feedback control of ribosome synthesis." J Bacteriol 185(20);6185-91. PMID: 14526030

Zaslaver06: Zaslaver A, Bren A, Ronen M, Itzkovitz S, Kikoin I, Shavit S, Liebermeister W, Surette MG, Alon U (2006). "A comprehensive library of fluorescent transcriptional reporters for Escherichia coli." Nat Methods 3(8);623-8. PMID: 16862137

Zengel94: Zengel JM, Lindahl L (1994). "Diverse mechanisms for regulating ribosomal protein synthesis in Escherichia coli." Prog Nucleic Acid Res Mol Biol 47;331-70. PMID: 7517053

Zhang02a: Zhang X, Dennis P, Ehrenberg M, Bremer H (2002). "Kinetic properties of rrn promoters in Escherichia coli." Biochimie 84(10);981-96. PMID: 12504278


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sun Dec 21, 2014, BIOCYC13B.