Metabolic Modeling Tutorial
registration ends
Sat Mar 7th, 2015
Metabolic Modeling Tutorial
registration ends
Sat Mar 7th, 2015
Metabolic Modeling Tutorial
registration ends
Sat Mar 7th, 2015
Metabolic Modeling Tutorial
registration ends
Sat Mar 7th, 2015
Metabolic Modeling Tutorial
registration ends
Sat Mar 7th, 2015
twitter

Escherichia coli K-12 substr. MG1655 Polypeptide: oxidoreductase, predicted membrane anchor subunit



Gene: ynfH Accession Numbers: G6848 (EcoCyc), b1590, ECK1585

Regulation Summary Diagram: ?

Component of: putative selenate reductase (summary available)

Summary:
YnfH contains eight potential transmembrane helices and is similar to DmsC, the membrane anchor subunit of the dimethyl sulfoxide reductase heterotrimer. When expressed together with DmsA and either DmsB or YnfG in a plasmid expression system, YnfH can form a complex with DmsA and DmsB/YnfG and support growth on DMSO [Lubitz03].

Locations: inner membrane

Map Position: [1,661,633 -> 1,662,487] (35.81 centisomes)
Length: 855 bp / 284 aa

Molecular Weight of Polypeptide: 30.524 kD (from nucleotide sequence)

Unification Links: ASAP:ABE-0005311 , EchoBASE:EB3607 , EcoGene:EG13846 , EcoliWiki:b1590 , OU-Microarray:b1590 , PortEco:ynfH , Protein Model Portal:P76173 , RefSeq:NP_416107 , RegulonDB:G6848 , String:511145.b1590 , UniProt:P76173

Relationship Links: InterPro:IN-FAMILY:IPR007059 , Pfam:IN-FAMILY:PF04976

Gene-Reaction Schematic: ?

Gene Class: UNCLASSIFIED


Enzymatic reaction of: aspartate ammonia-lyase (fumarate hydratase)

Synonyms: fumaric aminase, aspartase

EC Number: 4.3.1.1

L-aspartate <=> ammonia + fumarate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

The reaction is favored in the direction shown.

In Pathways: glutamine degradation III , glutamine degradation II , aspartate degradation


Enzymatic reaction of: fumarate hydratase

EC Number: 4.2.1.2

malate <=> fumarate + H2O

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

This reaction is reversible.

In Pathways: superpathway of glycolysis and TCA variant VIII , respiration (anaerobic) , mixed acid fermentation , pyruvate fermentation to propionate , phenylalanine degradation I , superpathway of glyoxylate cycle , aspartate degradation , TCA cycle variation VIII


Gene Local Context (not to scale): ?

Transcription Unit:

Notes:


References

Green04: Green ML, Karp PD (2004). "A Bayesian method for identifying missing enzymes in predicted metabolic pathway databases." BMC Bioinformatics 5;76. PMID: 15189570

Omara: Omara, W., Hodgson, D.A. "Unpublished."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Thu Mar 5, 2015, biocyc13.