|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Macromolecule Reactions → Polynucleotide-Reactions → RNA-Reactions → tRNA-Reactions|
EC Number: 18.104.22.168
In Pathway: L-selenocysteine biosynthesis I (bacteria)
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: L-seryl-tRNASec selenium transferase
Enzyme Commission Synonyms: L-selenocysteinyl-tRNASel synthase, L-selenocysteinyl-tRNASec synthase selenocysteine synthase, cysteinyl-tRNASec-selenium transferase
Enzyme Commission Summary:
A pyridoxal 5′-phosphate enzyme identified in Escherichia coli. Recognises specifically tRNASec-species. Binding of tRNASec also occurs in the absence of the seryl group. 2-Aminoacryloyl-tRNA, bound to the enzyme as an imine with the pyridoxal phosphate, is an intermediate in the reaction. Since the selenium atom replaces oxygen in serine, the product may also be referred to as L-selenoseryl-tRNASec. The symbol Sel has also been used for selenocysteine but Sec is preferred.
Citations: [Forchhammer91b ]
©2016 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493