|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
Enzymes and Genes:
D-malate / 3-isopropylmalate dehydrogenase (decarboxylating) : dmlA
3-isopropylmalate dehydrogenase : leuB
In Pathway: L-leucine biosynthesis
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
This is the third step in leucine biosynthesis after the fork from valine synthesis. It is an oxidative decarboxylation.
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