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Escherichia coli K-12 substr. MG1655 Reaction: [no EC number assigned]

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

Enzymes and Genes:
D-malate / 3-isopropylmalate dehydrogenase (decarboxylating) Inferred from experiment : dmlA
3-isopropylmalate dehydrogenase Inferred from experiment : leuB

In Pathway: L-leucine biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Summary:
This is the third step in leucine biosynthesis after the fork from valine synthesis. It is an oxidative decarboxylation.

Gene-Reaction Schematic: ?

Gene-Reaction Schematic


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Sat Mar 28, 2015, BIOCYC13A.