Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reaction: 3.1.26.5

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.1.26.5

Enzymes and Genes:
RNase P Inferred from experiment : rnpB , rnpA

In Pathway: tRNA processing

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Undetermined; a substrate lacks a chemical formula

Enzyme Commission Primary Name: ribonuclease P

Enzyme Commission Synonyms: RNase P

Summary:
This is the endonucleolytic cleavage of RNA to remove the excess 5' nucleotide from tRNA precursor, yielding the final 5' terminus of a mature tRNA.

Enzyme Commission Summary:
Endonucleolytic cleavage of RNA, removing 5-extranucleotides from tRNA precursor.

Citations: [Bikoff75, Bikoff75a, Robertson72]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:3.1.26.5 , ENZYME:EC:3.1.26.5 , IUBMB-ExplorEnz:EC:3.1.26.5


References

Bikoff75: Bikoff EK, Gefter ML (1975). "In vitro synthesis of transfer RNA. I. Purification of required components." J Biol Chem 250(16);6240-7. PMID: 1099089

Bikoff75a: Bikoff EK, LaRue BF, Gefter ML (1975). "In vitro synthesis of transfer RNA. II. Identification of required enzymatic activities." J Biol Chem 250(16);6248-55. PMID: 1099090

Robertson72: Robertson HD, Altman S, Smith JD (1972). "Purification and properties of a specific Escherichia coli ribonuclease which cleaves a tyrosine transfer ribonucleic acid presursor." J Biol Chem 247(16);5243-51. PMID: 4560501


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sun Nov 23, 2014, BIOCYC13A.