|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 220.127.116.11
In Pathway: tRNA processing
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Undetermined; a substrate lacks a chemical formula
Enzyme Commission Primary Name: ribonuclease P
Enzyme Commission Synonyms: RNase P
This is the endonucleolytic cleavage of RNA to remove the excess 5' nucleotide from tRNA precursor, yielding the final 5' terminus of a mature tRNA.
Enzyme Commission Summary:
Endonucleolytic cleavage of RNA, removing 5-extranucleotides from tRNA precursor.
Robertson72: Robertson HD, Altman S, Smith JD (1972). "Purification and properties of a specific Escherichia coli ribonuclease which cleaves a tyrosine transfer ribonucleic acid presursor." J Biol Chem 247(16);5243-51. PMID: 4560501
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