|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 126.96.36.199
In Pathway: tRNA processing
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Mass balance status: Marked as unbalanced.
Enzyme Commission Primary Name: ribonuclease P
Enzyme Commission Synonyms: RNase P
This is the endonucleolytic cleavage of RNA to remove the excess 5' nucleotide from tRNA precursor, yielding the final 5' terminus of a mature tRNA.
Enzyme Commission Summary:
Endonucleolytic cleavage of RNA, removing 5-extranucleotides from tRNA precursor.
Robertson72: Robertson HD, Altman S, Smith JD (1972). "Purification and properties of a specific Escherichia coli ribonuclease which cleaves a tyrosine transfer ribonucleic acid presursor." J Biol Chem 247(16);5243-51. PMID: 4560501
©2016 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493