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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reaction: 3.4.13.9

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.4.13.9

Enzymes and Genes:
proline dipeptidase Inferred from experiment : pepQ

Supersedes EC number: 3.4.3.7

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: Xaa-Pro dipeptidase

Enzyme Commission Synonyms: prolidase, imidodipeptidase, proline dipeptidase, peptidase D, γ-peptidase, X-Pro dipeptidase

Enzyme Commission Summary:
This enzyme catalyzes hydrolysis of Xaa-|-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.

A Mn2+-activated enzyme, in peptidase family M24 (methionyl aminopeptidase family); cytosolic from most animal tissues.

Citations: [DAVIS57, Sjostrom73, Baksi74, Browne83]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:3.4.13.9 , ENZYME:EC:3.4.13.9 , IUBMB-ExplorEnz:EC:3.4.13.9


References

Baksi74: Baksi K, Radhakrishnan AN (1974). "Purification and properties of prolidase (imidodipeptidase) from monkey small intestine." Indian J Biochem Biophys 11(1);7-11. PMID: 4435812

Browne83: Browne P, O'Cuinn G (1983). "The purification and characterization of a proline dipeptidase from guinea pig brain." J Biol Chem 258(10);6147-54. PMID: 6853481

DAVIS57: DAVIS NC, SMITH EL (1957). "Purification and some properties of prolidase of swine kidney." J Biol Chem 224(1);261-75. PMID: 13398404

Sjostrom73: Sjostrom H, Noren O, Josefsson L (1973). "Purification and specificity of pig intestinal prolidase." Biochim Biophys Acta 327(2);457-70. PMID: 4778946


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sun Dec 21, 2014, BIOCYC14B.