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Escherichia coli K-12 substr. MG1655 Reaction: 3.6.3.24


Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical ReactionsTransport Energised by P-P Bond Hydrolysis
Reactions Classified By Conversion TypeSimple ReactionsTransport ReactionsTransport Energised by P-P Bond Hydrolysis
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 3.6.3.24

Transporters and Genes:
Mg2+ / Ni2+ transporting ATPaseInferred by computational analysis: mgtA
nickel ABC transporterInferred from experimentInferred by computational analysis: nikD, nikE, nikB, nikC, nikA

Note that this reaction equation differs from the official Enzyme Commission reaction equations for this EC number.

Transport reaction diagram

Reaction Locations: inner membrane (sensu Gram-negative Bacteria)

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: nickel-transporting ATPase

Enzyme Commission Summary:
ABC-type (ATP-binding cassette-type) ATPase, characterised by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. A bacterial enzyme that imports Ni2+.

Citations: [Saier98, Hendricks97, Kuan95]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:3.6.3.24, ENZYME:EC:3.6.3.24, IUBMB-ExplorEnz:EC:3.6.3.24


References

Hendricks97: Hendricks JK, Mobley HL (1997). "Helicobacter pylori ABC transporter: effect of allelic exchange mutagenesis on urease activity." J Bacteriol 179(18);5892-902. PMID: 9294450

Kuan95: Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases." Res Microbiol 146(4);271-8. PMID: 7569321

Saier98: Saier MH (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya." Adv Microb Physiol 40;81-136. PMID: 9889977


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Sun Feb 14, 2016, biocyc13.