|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions → Transport Energized by Phosphoanhydride-Bond Hydrolysi|
|Reactions Classified By Conversion Type → Simple Reactions → Transport Reactions → Transport Energized by Phosphoanhydride-Bond Hydrolysi|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
Note that this reaction equation differs from the official Enzyme Commission reaction equations for this EC number.
Reaction Locations: inner membrane (sensu Gram-negative Bacteria)
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: iron-chelate-transporting ATPase
Enzyme Commission Synonyms:
Enzyme Commission Summary:
ABC-type (ATP-binding cassette-type) ATPase, characterised by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. A bacterial enzyme that imports Fe-enterobactin, Fe-dicitrate, Fe-hydroxamate and other siderophores.
Koster92: Koster W, Bohm B (1992). "Point mutations in two conserved glycine residues within the integral membrane protein FhuB affect iron(III) hydroxamate transport." Mol Gen Genet 232(3);399-407. PMID: 1588908
Kuan95: Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases." Res Microbiol 146(4);271-8. PMID: 7569321
Mademidis98: Mademidis A, Koster W (1998). "Transport activity of FhuA, FhuC, FhuD, and FhuB derivatives in a system free of polar effects, and stoichiometry of components involved in ferrichrome uptake." Mol Gen Genet 1998;258(1-2);156-65. PMID: 9613584
Shea91: Shea CM, McIntosh MA (1991). "Nucleotide sequence and genetic organization of the ferric enterobactin transport system: homology to other periplasmic binding protein-dependent systems in Escherichia coli." Mol Microbiol 1991;5(6);1415-28. PMID: 1838574
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