|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions → Transport Energised by P-P Bond Hydrolysis|
|Reactions Classified By Conversion Type → Simple Reactions → Transport Reactions → Transport Energised by P-P Bond Hydrolysis|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
Note that this reaction equation differs from the official Enzyme Commission reaction equations for this EC number.
Reaction Locations: inner membrane (sensu Gram-negative Bacteria)
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: iron-chelate-transporting ATPase
Enzyme Commission Synonyms:
Enzyme Commission Summary:
ABC-type (ATP-binding cassette-type) ATPase, characterised by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. A bacterial enzyme that imports Fe-enterobactin, Fe-dicitrate, Fe-hydroxamate and other siderophores.
Koster92: Koster W, Bohm B (1992). "Point mutations in two conserved glycine residues within the integral membrane protein FhuB affect iron(III) hydroxamate transport." Mol Gen Genet 232(3);399-407. PMID: 1588908
Kuan95: Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases." Res Microbiol 146(4);271-8. PMID: 7569321
Mademidis98: Mademidis A, Koster W (1998). "Transport activity of FhuA, FhuC, FhuD, and FhuB derivatives in a system free of polar effects, and stoichiometry of components involved in ferrichrome uptake." Mol Gen Genet 1998;258(1-2);156-65. PMID: 9613584
Shea91: Shea CM, McIntosh MA (1991). "Nucleotide sequence and genetic organization of the ferric enterobactin transport system: homology to other periplasmic binding protein-dependent systems in Escherichia coli." Mol Microbiol 1991;5(6);1415-28. PMID: 1838574
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