|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: acyl-CoA hydrolase
Enzyme Commission Synonyms: acyl coenzyme A thioesterase, acyl coenzyme A hydrolase, thioesterase B, thioesterase II, acyl-CoA thioesterase
Enzyme Commission Summary:
Broad specificity for medium- to long-chain acyl-CoA. Insensitive to NAD+ (cf. EC 22.214.171.124 ADP-dependent medium-chain-acyl-CoA hydrolase).
Instance reactions of [an acyl-CoA + H2O → a carboxylate + coenzyme A + H+] (126.96.36.199):
i1: (R)-3-hydroxybutanoyl-CoA + H2O → (R)-3-hydroxybutanoate + coenzyme A + H+ (no EC#)
i2: (S)-3-hydroxybutanoyl-CoA + H2O → (S)-3-hydroxybutanoate + coenzyme A + H+ (no EC#)
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