Escherichia coli K-12 substr. MG1655 Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:
NADPH-dependent aldehyde reductase Inferred from experiment : yqhD

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Instance reaction:
acetaldehyde + NADP+ + H2O → acetate + NADPH + 2 H+ (

Enzyme Commission Primary Name: aldehyde dehydrogenase (NADP+)

Enzyme Commission Synonyms: NADP-acetaldehyde dehydrogenase, NADP-dependent aldehyde dehydrogenase, aldehyde dehydrogenase (NADP)

Citations: [Seegmiller53]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Instance reaction of [an aldehyde + NADP+ + H2O → a carboxylate + NADPH + 2 H+] (
i3: acetaldehyde + NADP+ + H2O → acetate + NADPH + 2 H+ (

Instance reactions of [an alcohol + NADP+ = an aldehyde + NADPH + H+] (
i1: (S)-propane-1,2-diol + NADP+ = (S)-lactaldehyde + NADPH + H+ (1.1.1.-)

i2: (R)-propane-1,2-diol + NADP+ = (R)-lactaldehyde + NADPH + H+ (1.1.1.-)

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC:


Seegmiller53: Seegmiller JE (1953). "Triphosphopyridine nucleotide-linked aldehyde dehydrogenase from yeast." J Biol Chem 201(2);629-37. PMID: 13061400

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Tue Oct 6, 2015, biocyc13.