Escherichia coli K-12 substr. MG1655 Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:
aspartate transcarbamylase Inferred from experiment : pyrB , pyrI

In Pathway: UMP biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: aspartate carbamoyltransferase

Enzyme Commission Synonyms: aspartate carbamyltransferase, aspartic acid transcarbamoylase, aspartic carbamyltransferase, aspartic transcarbamylase, carbamylaspartotranskinase, L-aspartate transcarbamoylase, L-aspartate transcarbamylase, carbamoylaspartotranskinase, aspartate transcarbamylase, aspartate transcarbamoylase, ATCase

The first committed reaction, but the second step, in the biosynthesis of pyrimidine.

Citations: [LOWENSTEIN56]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC:


LOWENSTEIN56: LOWENSTEIN JM, COHEN PP (1956). "Studies on the biosynthesis of carbamylaspartic acid." J Biol Chem 220(1);57-70. PMID: 13319326

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Sat Mar 28, 2015, BIOCYC14B.