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Escherichia coli K-12 substr. MG1655 Reaction: 2.1.3.2


Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 2.1.3.2

Enzymes and Genes:
aspartate transcarbamylaseInferred from experiment: pyrB, pyrI

In Pathway: UMP biosynthesis

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: aspartate carbamoyltransferase

Enzyme Commission Synonyms: aspartate carbamyltransferase, aspartic acid transcarbamoylase, aspartic carbamyltransferase, aspartic transcarbamylase, carbamylaspartotranskinase, L-aspartate transcarbamoylase, L-aspartate transcarbamylase, carbamoylaspartotranskinase, aspartate transcarbamylase, aspartate transcarbamoylase, ATCase

Summary:
The first committed reaction, but the second step, in the biosynthesis of pyrimidine.

Citations: [LOWENSTEIN56]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:2.1.3.2, ENZYME:EC:2.1.3.2, IUBMB-ExplorEnz:EC:2.1.3.2


References

LOWENSTEIN56: LOWENSTEIN JM, COHEN PP (1956). "Studies on the biosynthesis of carbamylaspartic acid." J Biol Chem 220(1);57-70. PMID: 13319326


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Fri Apr 29, 2016, biocyc13.