Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reaction: 2.1.3.2

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.1.3.2

Enzymes and Genes:
aspartate transcarbamylase Inferred from experiment : pyrB , pyrI

In Pathway: UMP biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: aspartate carbamoyltransferase

Enzyme Commission Synonyms: aspartate carbamyltransferase, aspartic acid transcarbamoylase, aspartic carbamyltransferase, aspartic transcarbamylase, carbamylaspartotranskinase, L-aspartate transcarbamoylase, L-aspartate transcarbamylase, carbamoylaspartotranskinase, aspartate transcarbamylase, aspartate transcarbamoylase, ATCase

Summary:
The first committed reaction, but the second step, in the biosynthesis of pyrimidine.

Citations: [LOWENSTEIN56]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:2.1.3.2 , ENZYME:EC:2.1.3.2 , IUBMB-ExplorEnz:EC:2.1.3.2


References

LOWENSTEIN56: LOWENSTEIN JM, COHEN PP (1956). "Studies on the biosynthesis of carbamylaspartic acid." J Biol Chem 220(1);57-70. PMID: 13319326


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, biocyc14.