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Escherichia coli K-12 substr. MG1655 Reaction: 5.3.1.12

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 5.3.1.12

Enzymes and Genes:
D-glucuronate isomerase Inferred from experiment : uxaC

In Pathway: β-D-glucuronide and D-glucuronate degradation

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: glucuronate isomerase

Enzyme Commission Synonyms: uronic isomerase, uronate isomerase, D-glucuronate isomerase, uronic acid isomerase, D-glucuronate ketol-isomerase

Summary:
Part of the glucuronate pathway.

Enzyme Commission Summary:
Also converts D-galacturonate to D-tagaturonate.

Citations: [Ashwell60, Kilgore59]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:5.3.1.12 , ENZYME:EC:5.3.1.12 , IUBMB-ExplorEnz:EC:5.3.1.12


References

Ashwell60: Ashwell G, Wahba AJ, Hickman J (1960). "Uronic acid metabolism in bacteria. I. Purification and properties of uronic acid isomerase in Escherichia coli." J Biol Chem 1960;235(6):1559-1565. PMID: 13794771

Kilgore59: Kilgore WW, Starr MP (1959). "Catabolism of galacturonic and glucuronic acids by Erwinia carotovora." J Biol Chem 234;2227-35. PMID: 14409051


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Tue Apr 28, 2015, biocyc11.