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Escherichia coli K-12 substr. MG1655 Reaction: 5.3.1.12


Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 5.3.1.12

Enzymes and Genes:
D-glucuronate isomeraseInferred from experiment: uxaC

In Pathway: β-D-glucuronide and D-glucuronate degradation

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: glucuronate isomerase

Enzyme Commission Synonyms: uronic isomerase, uronate isomerase, D-glucuronate isomerase, uronic acid isomerase, D-glucuronate ketol-isomerase

Summary:
Part of the glucuronate pathway.

Enzyme Commission Summary:
Also converts D-galacturonate to D-tagaturonate.

Citations: [Ashwell60, Kilgore59]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:5.3.1.12, ENZYME:EC:5.3.1.12, IUBMB-ExplorEnz:EC:5.3.1.12


References

Ashwell60: Ashwell G, Wahba AJ, Hickman J (1960). "Uronic acid metabolism in bacteria. I. Purification and properties of uronic acid isomerase in Escherichia coli." J Biol Chem 1960;235(6):1559-1565. PMID: 13794771

Kilgore59: Kilgore WW, Starr MP (1959). "Catabolism of galacturonic and glucuronic acids by Erwinia carotovora." J Biol Chem 234;2227-35. PMID: 14409051


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Thu Feb 11, 2016, biocyc14.