Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reaction: 2.7.1.30

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.7.1.30

Enzymes and Genes:
glycerol kinase Inferred from experiment : glpK

In Pathway: glycerol degradation I

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: glycerol kinase

Enzyme Commission Synonyms: glycerokinase, GK, ATP:glycerol-3-phosphotransferase, glycerol kinase (phosphorylating), glyceric kinase

Summary:
This is the first reaction in the pathway for the utilization of glycerol as a carbon and energy source.

Enzyme Commission Summary:
Glycerone and L-glyceraldehyde can act as acceptors; UTP (and, in the case of the yeast enzyme, ITP and GTP) can act as donors.

Citations: [WIELAND57, BUBLITZ54, Thorner75]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:2.7.1.30 , ENZYME:EC:2.7.1.30 , IUBMB-ExplorEnz:EC:2.7.1.30


References

BUBLITZ54: BUBLITZ C, KENNEDY EP (1954). "Synthesis of phosphatides in isolated mitochondria. III. The enzymatic phosphorylation of glycerol." J Biol Chem 211(2);951-61. PMID: 13221600

Thorner75: Thorner JW (1975). "Glycerol kinase." Methods Enzymol 1975;42;148-56. PMID: 237175

WIELAND57: WIELAND O, SUYTER M (1957). "[Glycerokinase; isolation and properties of the enzyme]." Biochem Z 329(4);320-31. PMID: 13522709


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, BIOCYC14A.