Escherichia coli K-12 substr. MG1655 Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:
glycerol kinaseInferred from experiment: glpK

In Pathway: glycerol degradation I

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: glycerol kinase

Enzyme Commission Synonyms: glycerokinase, GK, ATP:glycerol-3-phosphotransferase, glycerol kinase (phosphorylating), glyceric kinase

This is the first reaction in the pathway for the utilization of glycerol as a carbon and energy source.

Enzyme Commission Summary:
Glycerone and L-glyceraldehyde can act as acceptors; UTP (and, in the case of the yeast enzyme, ITP and GTP) can act as donors.

Citations: [WIELAND57, BUBLITZ54, Thorner75]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


BUBLITZ54: BUBLITZ C, KENNEDY EP (1954). "Synthesis of phosphatides in isolated mitochondria. III. The enzymatic phosphorylation of glycerol." J Biol Chem 211(2);951-61. PMID: 13221600

Thorner75: Thorner JW (1975). "Glycerol kinase." Methods Enzymol 1975;42;148-56. PMID: 237175

WIELAND57: WIELAND O, SUYTER M (1957). "[Glycerokinase; isolation and properties of the enzyme]." Biochem Z 329(4);320-31. PMID: 13522709

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 20.0 (software by SRI International) on Fri May 6, 2016, BIOCYC13B.