Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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Escherichia coli K-12 substr. MG1655 Reaction: 2.7.1.30

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.7.1.30

Enzymes and Genes:
glycerol kinase Inferred from experiment : glpK

In Pathway: glycerol degradation I

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: glycerol kinase

Enzyme Commission Synonyms: glycerokinase, GK, ATP:glycerol-3-phosphotransferase, glycerol kinase (phosphorylating), glyceric kinase

Summary:
This is the first reaction in the pathway for the utilization of glycerol as a carbon and energy source.

Enzyme Commission Summary:
Glycerone and L-glyceraldehyde can act as acceptors; UTP (and, in the case of the yeast enzyme, ITP and GTP) can act as donors.

Citations: [WIELAND57, BUBLITZ54, Thorner75]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:2.7.1.30 , ENZYME:EC:2.7.1.30 , IUBMB-ExplorEnz:EC:2.7.1.30


References

BUBLITZ54: BUBLITZ C, KENNEDY EP (1954). "Synthesis of phosphatides in isolated mitochondria. III. The enzymatic phosphorylation of glycerol." J Biol Chem 211(2);951-61. PMID: 13221600

Thorner75: Thorner JW (1975). "Glycerol kinase." Methods Enzymol 1975;42;148-56. PMID: 237175

WIELAND57: WIELAND O, SUYTER M (1957). "[Glycerokinase; isolation and properties of the enzyme]." Biochem Z 329(4);320-31. PMID: 13522709


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, biocyc12.