Escherichia coli K-12 substr. MG1655 Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:
nucleoside di- and triphosphate hydrolase Inferred from experiment : nudJ
putative nucleoside (IDP) diphosphatase : yibQ

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: guanosine-diphosphatase

Enzyme Commission Synonyms: GDPase

Enzyme Commission Summary:
Also acts on UDP but not on other nucleoside diphosphates and triphosphates.

Citations: [Raychaudhuri85]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Instance reactions of [a nucleoside diphosphate + H2O → a nucleoside 5'-monophosphate + phosphate + H+] (
i1: UDP + H2O → UMP + phosphate + H+ (

i2: GDP + H2O → GMP + phosphate + H+ (
i3: CDP + H2O → CMP + phosphate + H+ (

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC:


Raychaudhuri85: Raychaudhuri P, Ghosh S, Maitra U (1985). "Purification and characterization of a guanosine diphosphatase activity from calf liver microsomal salt wash proteins." J Biol Chem 260(14);8306-11. PMID: 2989286

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Fri Oct 9, 2015, biocyc11.