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Metabolic Modeling Tutorial
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Escherichia coli K-12 substr. MG1655 Reaction: 3.6.1.42

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.6.1.42

Enzymes and Genes:
nucleoside di- and triphosphate hydrolase Inferred from experiment : nudJ
putative nucleoside (IDP) diphosphatase : yibQ

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: guanosine-diphosphatase

Enzyme Commission Synonyms: GDPase

Enzyme Commission Summary:
Also acts on UDP but not on other nucleoside diphosphates and triphosphates.

Citations: [Raychaudhuri85]

Gene-Reaction Schematic: ?

Instance reactions of [a nucleoside diphosphate + H2O → a nucleoside 5'-monophosphate + phosphate + H+] (3.6.1.6):
i1: GDP + H2O → GMP + phosphate + H+ (3.6.1.42)
i2: UDP + H2O → UMP + phosphate + H+ (3.6.1.6)

i3: CDP + H2O → CMP + phosphate + H+ (3.6.1.6)

Relationship Links: BRENDA:EC:3.6.1.42 , ENZYME:EC:3.6.1.42 , IUBMB-ExplorEnz:EC:3.6.1.42


References

Raychaudhuri85: Raychaudhuri P, Ghosh S, Maitra U (1985). "Purification and characterization of a guanosine diphosphatase activity from calf liver microsomal salt wash proteins." J Biol Chem 260(14);8306-11. PMID: 2989286


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sat Nov 22, 2014, biocyc13.