Escherichia coli K-12 substr. MG1655 Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:
nucleoside di- and triphosphate hydrolaseInferred from experiment: nudJ
putative nucleoside (IDP) diphosphatase: yibQ

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: guanosine-diphosphatase

Enzyme Commission Synonyms: GDPase

Enzyme Commission Summary:
Also acts on UDP but not on other nucleoside diphosphates and triphosphates.

Citations: [Raychaudhuri85]

Gene-Reaction Schematic

Gene-Reaction Schematic

Instance reactions of [a nucleoside diphosphate + H2O → a nucleoside 5'-monophosphate + phosphate + H+] (
i1: GDP + H2O → GMP + phosphate + H+ (
i2: UDP + H2O → UMP + phosphate + H+ (

i3: CDP + H2O → CMP + phosphate + H+ (

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Raychaudhuri85: Raychaudhuri P, Ghosh S, Maitra U (1985). "Purification and characterization of a guanosine diphosphatase activity from calf liver microsomal salt wash proteins." J Biol Chem 260(14);8306-11. PMID: 2989286

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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