Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reaction: 6.1.1.6

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Macromolecule Reactions Polynucleotide-Reactions RNA-Reactions tRNA-Reactions tRNA-Charging-Reactions

EC Number: 6.1.1.6

Enzymes and Genes:
lysyl-tRNA synthetase, constitutive Inferred from experiment : lysS
lysyl-tRNA synthetase Inferred from experiment : lysU

In Pathway: tRNA charging

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: lysine—tRNA ligase

Enzyme Commission Synonyms: lysyl-tRNA synθse, lysyl-transfer ribonucleate synθse, lysyl-transfer RNA synθse, L-lysine-transfer RNA ligase, lysine-tRNA synθse, lysine translase

Citations: [ALLEN60, Chlumecka69, Lagerkvist72, Stern65]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:6.1.1.6 , ENZYME:EC:6.1.1.6 , IUBMB-ExplorEnz:EC:6.1.1.6


References

ALLEN60: ALLEN EH, GLASSMAN E, SCHWEET RS (1960). "Incorporation of amino acids into ribonucleic acid. I. The role of activating enzymes." J Biol Chem 235;1061-7. PMID: 13792726

Chlumecka69: Chlumecka V, Von Tigerstrom M, D'Obrenan P, Smith CJ (1969). "Purification and properties of lysyl transfer ribonucleic acid synthetase from bakers' yeast." J Biol Chem 244(20);5481-8. PMID: 4310598

Lagerkvist72: Lagerkvist U, Rymo L, Lindqvist O, Andersson E (1972). "Some properties of crystals of lysine transfer ribonucleic acid ligase from yeast." J Biol Chem 247(12);3897-9. PMID: 4555953

Stern65: Stern R, Mehler AH (1965). "Lysyl-sRNA synthetase from Escherichia coli." Biochem Z 342(4);400-9. PMID: 4284804


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, BIOCYC14A.