|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Macromolecule Reactions → Polynucleotide-Reactions → RNA-Reactions → tRNA-Reactions → tRNA-Charging-Reactions|
EC Number: 22.214.171.124
In Pathway: tRNA charging
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: lysine—tRNA ligase
Enzyme Commission Synonyms: lysyl-tRNA synθse, lysyl-transfer ribonucleate synθse, lysyl-transfer RNA synθse, L-lysine-transfer RNA ligase, lysine-tRNA synθse, lysine translase
Instance reaction of [an acyl-carrier protein + coenzyme A → adenosine 3',5'-bisphosphate + a holo-[acyl-carrier protein] + H+] (126.96.36.199):
i1: [EntB aryl-carrier protein] + coenzyme A → a holo-[EntB isochorismatase/aryl-carrier protein] + adenosine 3',5'-bisphosphate + H+ (188.8.131.52)
Chlumecka69: Chlumecka V, Von Tigerstrom M, D'Obrenan P, Smith CJ (1969). "Purification and properties of lysyl transfer ribonucleic acid synthetase from bakers' yeast." J Biol Chem 244(20);5481-8. PMID: 4310598
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