|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 220.127.116.11
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: maltose O-acetyltransferase
Enzyme Commission Synonyms: maltose transacetylase, maltose O-acetyltransferase, MAT
This reaction acetylates free sugars in the cell, perhaps playing a detoxifying role.
Enzyme Commission Summary:
Not identical with EC 18.104.22.168, galactoside O-acetyltransferase. The acetyl group is added exclusively to the C6 position of glucose and to the C6 position of the non-reducing glucose residue of maltose [Lo03]. Other substrates of this enzyme are glucose, which is a better substrate than maltose [Brand91], and mannose and frucose, which are poorer substrates than maltose [Brand91]. Isopropyl-β-thio-galactose, which is a good substrate for EC 22.214.171.124 is a poor substrate for this enzyme [Lo03].
Brand91: Brand B, Boos W (1991). "Maltose transacetylase of Escherichia coli. Mapping and cloning of its structural, gene, mac, and characterization of the enzyme as a dimer of identical polypeptides with a molecular weight of 20,000." J Biol Chem 1991;266(21);14113-8. PMID: 1856235
Lo03: Lo Leggio L, Dal Degan F, Poulsen P, Andersen SM, Larsen S (2003). "The structure and specificity of Escherichia coli maltose acetyltransferase give new insight into the LacA family of acyltransferases." Biochemistry 42(18);5225-35. PMID: 12731863
©2014 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493