Escherichia coli K-12 substr. MG1655 Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:
methylglyoxal synthaseInferred from experiment: mgsA

Supersedes EC number:

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: methylglyoxal synthase

Enzyme Commission Synonyms: methylglyoxal synthetase, glycerone-phosphate phospho-lyase

Enzyme Commission Summary:
Does not act on D-glyceraldehyde 3-phosphate.

Citations: [Ray81, Hopper71, Cooper70]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Cooper70: Cooper RA, Anderson A (1970). "The formation and catabolism of methylglyoxal during glycolysis in Escherichia coli." FEBS Lett 11(4);273-276. PMID: 11945504

Hopper71: Hopper DJ, Cooper RA (1971). "The regulation of Escherichia coli methylglyoxal synthase; a new control site in glycolysis?." FEBS Lett 13(4);213-216. PMID: 11945670

Ray81: Ray S, Ray M (1981). "Isolation of methylglyoxal synthase from goat liver." J Biol Chem 256(12);6230-3. PMID: 7240200

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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