|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
In Pathway: N10-formyl-tetrahydrofolate biosynthesis
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Mass balance status: Balanced.
Enzyme Commission Primary Name: methylenetetrahydrofolate dehydrogenase (NADP+)
Enzyme Commission Synonyms: N5,N10-methylenetetrahydrofolate dehydrogenase, 5,10-methylenetetrahydrofolate:NADP oxidoreductase, 5,10-methylenetetrahydrofolate dehydrogenase, methylenetetrahydrofolate dehydrogenase, methylenetetrahydrofolate dehydrogenase (NADP)
Enzyme Commission Summary:
This reaction is involved in folic acid synthesis and is necessary for the biosynthesis of purines, thymydylate, methionine, histidine, pantothenate and formyl tRNA-MET.
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