|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 220.127.116.11
In Pathway: NAD biosynthesis I (from aspartate)
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: NAD+ synthase
Enzyme Commission Synonyms: NAD synthetase, NAD synthase, nicotinamide adenine dinucleotide synthetase, diphosphopyridine nucleotide synthetase
A reaction in the biosynthesis of NAD. Glutamine can also serve as an amido group donor.
Enzyme Commission Summary:
L-Glutamine also acts, more slowly, as amido-donor [cf. EC 18.104.22.168].
Spencer67: Spencer RL, Preiss J (1967). "Biosynthesis of diphosphopyridine nucleotide. The purification and the properties of diphospyridine nucleotide synthetase from Escherichia coli b." J Biol Chem 1967;242(3);385-92. PMID: 4290215
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