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Escherichia coli K-12 substr. MG1655 Reaction: 6.3.1.5

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 6.3.1.5

Enzymes and Genes:
NAD synthetase, NH3-dependent Inferred from experiment : nadE

In Pathway: NAD biosynthesis I (from aspartate)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: NAD+ synthase

Enzyme Commission Synonyms: NAD synthetase, NAD synthase, nicotinamide adenine dinucleotide synthetase, diphosphopyridine nucleotide synthetase

Summary:
A reaction in the biosynthesis of NAD. Glutamine can also serve as an amido group donor.

Enzyme Commission Summary:
L-Glutamine also acts, more slowly, as amido-donor [cf. EC 6.3.5.1].

Citations: [Spencer67]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:6.3.1.5 , ENZYME:EC:6.3.1.5 , IUBMB-ExplorEnz:EC:6.3.1.5


References

Spencer67: Spencer RL, Preiss J (1967). "Biosynthesis of diphosphopyridine nucleotide. The purification and the properties of diphospyridine nucleotide synthetase from Escherichia coli b." J Biol Chem 1967;242(3);385-92. PMID: 4290215


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Thu Aug 27, 2015, biocyc13.