Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reaction: 6.3.1.5

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 6.3.1.5

Enzymes and Genes:
NAD synthetase, NH3-dependent Inferred from experiment : nadE

In Pathway: NAD biosynthesis I (from aspartate)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: NAD+ synthase

Enzyme Commission Synonyms: NAD synθse, NAD synthase, nicotinamide adenine dinucleotide synθse, diphosphopyridine nucleotide synθse

Summary:
A reaction in the biosynthesis of NAD. Glutamine can also serve as an amido group donor.

Enzyme Commission Summary:
L-Glutamine also acts, more slowly, as amido-donor [cf. EC 6.3.5.1].

Citations: [Spencer67]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:6.3.1.5 , ENZYME:EC:6.3.1.5 , IUBMB-ExplorEnz:EC:6.3.1.5


References

Spencer67: Spencer RL, Preiss J (1967). "Biosynthesis of diphosphopyridine nucleotide. The purification and the properties of diphospyridine nucleotide synthetase from Escherichia coli b." J Biol Chem 1967;242(3);385-92. PMID: 4290215


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, BIOCYC13A.