Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reaction: 2.7.9.2

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.7.9.2

Enzymes and Genes:
phosphoenolpyruvate synthetase Inferred from experiment : ppsA

In Pathway: gluconeogenesis I , glycolysis II (from fructose-6P) , glycolysis I (from glucose-6P)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: pyruvate, water dikinase

Enzyme Commission Synonyms: pyruvate-water dikinase (phosphorylating), PEP synθse, phosphoenolpyruvate synthase, phoephoenolpyruvate synθse, phosphoenolpyruvic synthase, phosphopyruvate synθse

Summary:
A reaction of gluconeogenesis.

Enzyme Commission Summary:
A manganese protein.

Citations: [Cooper65, Berman70a, Berman70]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:2.7.9.2 , ENZYME:EC:2.7.9.2 , IUBMB-ExplorEnz:EC:2.7.9.2


References

Berman70: Berman KM, Cohn M (1970). "Phosphoenolpyruvate synthetase of Escherichia coli. Purification, some properties, and the role of divalent metal ions." J Biol Chem 245(20);5309-18. PMID: 4319237

Berman70a: Berman KM, Cohn M (1970). "Phosphoenolpyruvate synthetase. Partial reactions studied with adenosine triphosphate analogues and the inorganic phosphate-H2 18O exchange reaction." J Biol Chem 245(20);5319-25. PMID: 4319238

Cooper65: Cooper RA, Kornberg HL (1965). "Net formation of phosphoenolpyruvate from pyruvate by Escherichia coli." Biochim Biophys Acta 104(2);618-20. PMID: 5322808


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Fri Nov 28, 2014, BIOCYC13B.