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Escherichia coli K-12 substr. MG1655 Reaction: 2.3.1.8

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.3.1.8

Enzymes and Genes:
phosphate acetyltransferase Inferred from experiment : eutD
phosphate acetyltransferase Inferred from experiment : pta

In Pathway: acetate formation from acetyl-CoA I , mixed acid fermentation

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: phosphate acetyltransferase

Enzyme Commission Synonyms: phosphotransacetylase, phosphoacylase, PTA

Summary:
The first reaction in the conversion of acetyl-CoA to acetate.

Enzyme Commission Summary:
Also acts with other short-chain acyl-CoAs.

Citations: [STADTMAN52, BERGMEYER63]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:2.3.1.8 , ENZYME:EC:2.3.1.8 , IUBMB-ExplorEnz:EC:2.3.1.8


References

BERGMEYER63: BERGMEYER HU, HOLZ G, KLOTZSCH H, LANG G (1963). "[PHOSPHOTRANSACETYLASE FROM CLOSTRIDIUM KLUYVERI. CULTURE OF THE BACTERIUM, ISOLATION, CRYSTALLIZATION AND PROPERTIES OF THE ENZYME]." Biochem Z 338;114-21. PMID: 14087284

STADTMAN52: STADTMAN ER (1952). "The purification and properties of phosphotransacetylase." J Biol Chem 196(2);527-34. PMID: 12980995


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Wed Jul 29, 2015, BIOCYC13B.