twitter

Escherichia coli K-12 substr. MG1655 Reaction: 2.3.1.8


Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 2.3.1.8

Enzymes and Genes:
phosphate acetyltransferaseInferred from experiment: eutD
phosphate acetyltransferaseInferred from experiment: pta

In Pathway: acetate formation from acetyl-CoA I, mixed acid fermentation

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: phosphate acetyltransferase

Enzyme Commission Synonyms: phosphotransacetylase, phosphoacylase, PTA

Summary:
The first reaction in the conversion of acetyl-CoA to acetate.

Enzyme Commission Summary:
Also acts with other short-chain acyl-CoAs.

Citations: [STADTMAN52, Bergmeyer63]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:2.3.1.8, ENZYME:EC:2.3.1.8, IUBMB-ExplorEnz:EC:2.3.1.8


References

Bergmeyer63: Bergmeyer, H.U., Holz, G., Klotzsch, H., Lang, G. (1963). "[Phosphotransacetylase from Clostridium kluyveri. Culture of the bacterium, isolation, crystallization and properties of the enzyme.]." Biochem Z 338;114-21. PMID: 14087284

STADTMAN52: STADTMAN ER (1952). "The purification and properties of phosphotransacetylase." J Biol Chem 196(2);527-34. PMID: 12980995


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 20.0 (software by SRI International) on Fri May 6, 2016, BIOCYC14.