Escherichia coli K-12 substr. MG1655 Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:
phosphoglycerate kinaseInferred from experiment: pgk

In Pathway: gluconeogenesis I, glycolysis II (from fructose 6-phosphate), glycolysis I (from glucose 6-phosphate)

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: phosphoglycerate kinase

Enzyme Commission Synonyms: PGK, 3-PGK, ATP-3-phospho-D-glycerate-1-phosphotransferase, ATP:D-3-phosphoglycerate 1-phosphotransferase, 3-phosphoglycerate kinase, 3-phosphoglycerate phosphokinase, 3-phosphoglyceric acid kinase, 3-phosphoglyceric acid phosphokinase, 3-phosphoglyceric kinase, glycerate 3-phosphate kinase, glycerophosphate kinase, phosphoglyceric acid kinase, phosphoglyceric kinase, phosphoglycerokinase

In this reaction a phosphoryl group is transferred from the acyl phosphate of 1,3 diphosphoglycerate to ADP thereby forming ATP and 3-phosphoglycerate. [Watson90]

Citations: [HASHIMOTO62, AXELROD53, RAO61]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


AXELROD53: AXELROD B, BANDURSKI RS (1953). "Phosphoglyceryl kinase in higher plants." J Biol Chem 204(2);939-48. PMID: 13117871

HASHIMOTO62: HASHIMOTO T, YOSHIKAWA H (1962). "Crystalline phosphoglycerate kinase from human erythrocytes." Biochim Biophys Acta 65;355-7. PMID: 13960866

RAO61: RAO DR, OESPER P (1961). "Purification and properties of muscle phosphoglycerate kinase." Biochem J 81;405-11. PMID: 14490315

Watson90: Watson HC, Littlechild JA (1990). "Isoenzymes of phosphoglycerate kinase: evolutionary conservation of the structure of this glycolytic enzyme." Biochem Soc Trans 1990;18(2);187-90. PMID: 2379683

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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