|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 184.108.40.206
In Pathway: L-phenylalanine biosynthesis I
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: prephenate dehydratase
Enzyme Commission Synonyms: prephenate hydro-lyase (decarboxylating)
This is the second reaction after chorismate in the biosynthesis of phenylalanine. It differs from the corresponding step in the biosynthesis of tyrosine in that it is a dehydratase, not a dehydrogenase.
Enzyme Commission Summary:
This enzyme in the enteric bacteria also possesses chorismate mutase ( EC 220.127.116.11) activity, and converts chorismate into prephenate.
Cotton65: Cotton RG, Gibson F (1965). "The biosynthesis of phenylalanine and tyrosine; enzymes converting chorismic acid into prephenic acid and their relationships to prephenate dehydratase and prephenate dehydrogenase." Biochim Biophys Acta 100;76-88. PMID: 14323651
©2016 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493