|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 184.108.40.206
220.127.116.11: cyanate + hydrogen carbonate + 3 H+ → ammonium + 2 CO2
In Pathway: cyanate degradation
Supersedes EC numbers: 18.104.22.168, 22.214.171.124
Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: cyanase
Enzyme Commission Synonyms: cyanate lyase, cyanate hydrolase, cyanate aminohydrolase, cyanate C-N-lyase, cyanate hydratase
Enzyme Commission Summary:
This enzyme, which is found in bacteria and plants, is used to decompose cyanate, which can be used as the sole source of nitrogen [Kozliak95, Walsh00]. Reaction (1) can be considered as the reverse of 'carbamate = cyanate + H2O', where this is assisted by reaction with bicarbonate and carbon dioxide [Johnson87a], and hence is classified in sub-subclass 4.2.1. Bicarbonate functions as a recycling substrate [Johnson87a].
Walsh00: Walsh MA, Otwinowski Z, Perrakis A, Anderson PM, Joachimiak A (2000). "Structure of cyanase reveals that a novel dimeric and decameric arrangement of subunits is required for formation of the enzyme active site." Structure 8(5);505-14. PMID: 10801492
©2016 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493