Escherichia coli K-12 substr. MG1655 Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateMacromolecule ReactionsPolynucleotide-ReactionsRNA-Reactions

EC Number:

Enzymes and Genes:
16S rRNA m2G1207 methyltransferaseInferred from experiment: rsmC

Supersedes EC number:

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 16S rRNA (guanine1207-N2)-methyltransferase

Enzyme Commission Synonyms: m2G1207 methyltransferase

Enzyme Commission Summary:
The enzyme reacts well with 30S subunits reconstituted from 16S RNA transcripts and 30S proteins but is almost inactive with the corresponding free RNA [Tscherne99a]. The enzyme specifically methylates guanine1207 at N2 in 16S rRNA.

Citations: [Sunita07]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:

Created 09-Aug-2010 by Kothari A, SRI International


Sunita07: Sunita S, Purta E, Durawa M, Tkaczuk KL, Swaathi J, Bujnicki JM, Sivaraman J (2007). "Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC." Nucleic Acids Res 35(13);4264-74. PMID: 17576679

Tscherne99a: Tscherne JS, Nurse K, Popienick P, Ofengand J (1999). "Purification, cloning, and characterization of the 16 S RNA m2G1207 methyltransferase from Escherichia coli." J Biol Chem 274(2);924-9. PMID: 9873033

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Wed Nov 25, 2015, biocyc14.