|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Macromolecule Reactions → Polynucleotide-Reactions → RNA-Reactions|
EC Number: 220.127.116.11
Supersedes EC number: 18.104.22.168
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 16S rRNA (guanine1207-N2)-methyltransferase
Enzyme Commission Synonyms: m2G1207 methyltransferase
Enzyme Commission Summary:
The enzyme reacts well with 30S subunits reconstituted from 16S RNA transcripts and 30S proteins but is almost inactive with the corresponding free RNA [Tscherne99]. The enzyme specifically methylates guanine1207 at N2 in 16S rRNA.
Sunita07: Sunita S, Purta E, Durawa M, Tkaczuk KL, Swaathi J, Bujnicki JM, Sivaraman J (2007). "Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC." Nucleic Acids Res 35(13);4264-74. PMID: 17576679
Tscherne99: Tscherne JS, Nurse K, Popienick P, Ofengand J (1999). "Purification, cloning, and characterization of the 16 S RNA m2G1207 methyltransferase from Escherichia coli." J Biol Chem 274(2);924-9. PMID: 9873033
©2014 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493