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Escherichia coli K-12 substr. MG1655 Reaction: 2.1.1.189

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Macromolecule Reactions Polynucleotide-Reactions RNA-Reactions

EC Number: 2.1.1.189

Enzymes and Genes:
23S rRNA m5U747 methyltransferase Inferred from experiment : rlmC

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 23S rRNA (uracil747-C5)-methyltransferase

Enzyme Commission Synonyms: YbjF, RumB, RNA uridine methyltransferase B

Enzyme Commission Summary:
The enzyme specifically methylates uracil747 at C5 in 23S rRNA.

Citations: [Madsen03]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:2.1.1.189 , ENZYME:EC:2.1.1.189 , IUBMB-ExplorEnz:EC:2.1.1.189

Credits:
Created 11-Aug-2010 by Kothari A , SRI International


References

Madsen03: Madsen CT, Mengel-Jorgensen J, Kirpekar F, Douthwaite S (2003). "Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry." Nucleic Acids Res 31(16);4738-46. PMID: 12907714


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Fri May 29, 2015, biocyc14.