|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Macromolecule Reactions → Polynucleotide-Reactions → RNA-Reactions|
EC Number: 22.214.171.124
Supersedes EC number: 126.96.36.199
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 23S rRNA (guanine1835-N2)-methyltransferase
Enzyme Commission Synonyms: ygjO (gene name), rlmG (gene name), ribosomal RNA large subunit methyltransferase G
Enzyme Commission Summary:
The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate [Sergiev06]. The enzyme specifically methylates guanine1835 at N2 in 23S rRNA.
Sergiev06: Sergiev PV, Lesnyak DV, Bogdanov AA, Dontsova OA (2006). "Identification of Escherichia coli m2G methyltransferases: II. The ygjO gene encodes a methyltransferase specific for G1835 of the 23 S rRNA." J Mol Biol 364(1):26-31. PMID: 17010380
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