Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
twitter

Escherichia coli K-12 substr. MG1655 Reaction: 2.1.1.174

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Macromolecule Reactions Polynucleotide-Reactions RNA-Reactions

EC Number: 2.1.1.174

Enzymes and Genes:
23S rRNA m2G1835 methyltransferase Inferred from experiment : rlmG

Supersedes EC number: 2.1.1.52

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 23S rRNA (guanine1835-N2)-methyltransferase

Enzyme Commission Synonyms: ygjO (gene name), rlmG (gene name), ribosomal RNA large subunit methyltransferase G

Enzyme Commission Summary:
The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate [Sergiev06]. The enzyme specifically methylates guanine1835 at N2 in 23S rRNA.

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:2.1.1.174 , ENZYME:EC:2.1.1.174 , IUBMB-ExplorEnz:EC:2.1.1.174

Credits:
Created 23-Aug-2010 by Kothari A , SRI International


References

Sergiev06: Sergiev PV, Lesnyak DV, Bogdanov AA, Dontsova OA (2006). "Identification of Escherichia coli m2G methyltransferases: II. The ygjO gene encodes a methyltransferase specific for G1835 of the 23 S rRNA." J Mol Biol 364(1):26-31. PMID: 17010380


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Wed Nov 26, 2014, biocyc13.