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Escherichia coli K-12 substr. MG1655 Reaction: 2.1.1.198


Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateMacromolecule ReactionsPolynucleotide-ReactionsRNA-Reactions

EC Number: 2.1.1.198

Enzymes and Genes:
16S rRNA 2'-O-ribose C1402 methyltransferaseInferred from experiment: rsmI

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 16S rRNA (cytidine1402-2′-O)-methyltransferase

Enzyme Commission Synonyms: RsmI, YraL

Enzyme Commission Summary:
RsmI catalyses the 2-O-methylation of cytosine1402 and RsmH ( EC 2.1.1.199) catalyses the N4-methylation of cytosine1402 in 16S rRNA. Both methylations are necessary for efficient translation initiation at the UUG and GUG codons.

Citations: [Kimura10]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:2.1.1.198, ENZYME:EC:2.1.1.198, IUBMB-ExplorEnz:EC:2.1.1.198

Credits:
Created 24-Aug-2010 by Kothari A, SRI International


References

Kimura10: Kimura S, Suzuki T (2010). "Fine-tuning of the ribosomal decoding center by conserved methyl-modifications in the Escherichia coli 16S rRNA." Nucleic Acids Res 38(4):1341-52. PMID: 19965768


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Fri Apr 29, 2016, biocyc13.