|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Macromolecule Reactions → Polynucleotide-Reactions → RNA-Reactions|
EC Number: 184.108.40.206
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 23S rRNA (uridine2552-2′-O)-methyltransferase
Enzyme Commission Synonyms: Um(2552) 23S ribosomal RNA methyltransferase, heat shock protein RrmJ, RrmJ, FTSJ, Um2552 methyltransferase
Enzyme Commission Summary:
The enzyme catalyses the 2-O-methylation of the universally conserved uridine2552 in the A loop of 23S rRNA [Bugl00].
Caldas00a: Caldas T, Binet E, Bouloc P, Costa A, Desgres J, Richarme G (2000). "The FtsJ/RrmJ heat shock protein of Escherichia coli is a 23 S ribosomal RNA methyltransferase." J Biol Chem 275(22);16414-9. PMID: 10748051
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