|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Macromolecule Reactions → Polynucleotide-Reactions → RNA-Reactions|
EC Number: 22.214.171.124
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 23S rRNA (uridine2552-2′-O)-methyltransferase
Enzyme Commission Synonyms: Um(2552) 23S ribosomal RNA methyltransferase, heat shock protein RrmJ, RrmJ, FTSJ, Um2552 methyltransferase
Enzyme Commission Summary:
The enzyme catalyses the 2-O-methylation of the universally conserved uridine2552 in the A loop of 23S rRNA [Bugl00].
Caldas00: Caldas T, Binet E, Bouloc P, Costa A, Desgres J, Richarme G (2000). "The FtsJ/RrmJ heat shock protein of Escherichia coli is a 23 S ribosomal RNA methyltransferase." J Biol Chem 275(22);16414-9. PMID: 10748051
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