|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Macromolecule Reactions → Polynucleotide-Reactions → RNA-Reactions → tRNA-Reactions|
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name for 188.8.131.52: tRNA (cytidine32/uridine32-2′-O)-methyltransferase
Enzyme Commission Synonyms for 184.108.40.206: YfhQ, tRNA:Cm32/Um32 methyltransferase, TrMet(Xm32), TrmJ
Enzyme Commission Primary Name for 220.127.116.11: tRNA (cytidine32/guanosine34-2′-O)-methyltransferase
Enzyme Commission Synonyms for 18.104.22.168: Trm7p
Enzyme Commission Summary for 22.214.171.124:
In Escherichia coli YfhQ is the only methyltransferase responsible for the formation of 2'-O-methylcytidine32 in tRNA. No methylation of cytosine34 in tRNALeu(CAA). In vitro the enzyme 2'-O-methylates cytidine34 of tRNASer1 and uridine32 of tRNAGln2.
Enzyme Commission Summary for 126.96.36.199:
The enzyme from Saccharomyces cerevisiae catalyses the formation of 2'-O-methylnucleotides at positions 32 and 34 of the yeast tRNAPhe, tRNATrp and, possibly, tRNALeu.
Pintard02: Pintard L, Lecointe F, Bujnicki JM, Bonnerot C, Grosjean H, Lapeyre B (2002). "Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop." EMBO J 21(7);1811-20. PMID: 11927565
Purta06: Purta E, van Vliet F, Tkaczuk KL, Dunin-Horkawicz S, Mori H, Droogmans L, Bujnicki JM (2006). "The yfhQ gene of Escherichia coli encodes a tRNA:Cm32/Um32 methyltransferase." BMC Mol Biol 7(1);23. PMID: 16848900
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