|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 220.127.116.11
In Pathway: molybdenum cofactor biosynthesis
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: molybdopterin adenylyltransferase
Enzyme Commission Synonyms: MogA, Cnx1 (ambiguous)
Enzyme Commission Summary:
Catalyses the activation of molybdopterin for molybdenum insertion. In eukaryotes, this reaction is catalysed by the C-terminal domain of a fusion protein that also includes molybdopterin molybdotransferase ( EC 18.104.22.168). The reaction requires a divalent cation such as Mg2+ or Mn2+.
Kuper00: Kuper J, Palmer T, Mendel RR, Schwarz G (2000). "Mutations in the molybdenum cofactor biosynthetic protein Cnx1G from Arabidopsis thaliana define functions for molybdopterin binding, molybdenum insertion, and molybdenum cofactor stabilization." Proc Natl Acad Sci U S A 97(12);6475-80. PMID: 10823911
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