|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 188.8.131.52
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: trans-aconitate 2-methyltransferase
Enzyme Commission Summary:
Also catalyzes the formation of the methyl monoester of cis- aconitate, isocitrate and citrate, but more slowly.
While the enzyme from Escherichia coli forms (E)-3- (methoxycarbonyl)-pent-2-enedioate as the product, that from Saccharomyces cerevisiae forms (E)-2-(methoxycarbonylmethyl) butenedioate and is therefore classified as a separate enzyme (cf. EC 184.108.40.206).
Cai01a: Cai H, Dumlao D, Katz JE, Clarke S (2001). "Identification of the gene and characterization of the activity of the trans-aconitate methyltransferase from Saccharomyces cerevisiae." Biochemistry 40(45);13699-709. PMID: 11695919
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