|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Mass balance status: Balanced.
Enzyme Commission Primary Name: trans-aconitate 2-methyltransferase
Enzyme Commission Summary:
Also catalyzes the formation of the methyl monoester of cis- aconitate, isocitrate and citrate, but more slowly.
While the enzyme from Escherichia coli forms (E)-3- (methoxycarbonyl)-pent-2-enedioate as the product, that from Saccharomyces cerevisiae forms (E)-2-(methoxycarbonylmethyl) butenedioate and is therefore classified as a separate enzyme (cf. EC 22.214.171.124).
Cai01a: Cai H, Dumlao D, Katz JE, Clarke S (2001). "Identification of the gene and characterization of the activity of the trans-aconitate methyltransferase from Saccharomyces cerevisiae." Biochemistry 40(45);13699-709. PMID: 11695919
©2015 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493