|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 188.8.131.52
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Direct generic reaction:
a purine ribonucleoside + phosphate ↔ a purine base + α-D-ribose-1-phosphate (184.108.40.206)
Enzyme Commission Primary Name: guanosine phosphorylase
Enzyme Commission Summary:
This enzyme has been defined based on a single publication of an enzyme from rabbit bone marrow that appears to be highly specific for guanosine and deoxyguanosine [Yamada61]. Most enzymes that are known to catalyze this reaction, such as the human purine nucleoside phosphorylase, can accept other purines as well, and thus were attributed to a specific case of the more general enzyme EC 220.127.116.11, ( guanosine + phosphate ↔ guanine + α-D-ribose-1-phosphate).
Instance reactions of [a purine ribonucleoside + phosphate ↔ a purine base + α-D-ribose-1-phosphate] (18.104.22.168):
i1: inosine + phosphate ↔ α-D-ribose-1-phosphate + hypoxanthine (22.214.171.124)
i2: guanosine + phosphate ↔ α-D-ribose-1-phosphate + guanine (126.96.36.199)
i3: adenosine + phosphate ↔ α-D-ribose-1-phosphate + adenine (188.8.131.52)
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