|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Direct generic reaction:
a purine ribonucleoside + phosphate ↔ a purine base + α-D-ribose-1-phosphate (22.214.171.124)
Enzyme Commission Primary Name: guanosine phosphorylase
Enzyme Commission Summary:
This enzyme has been defined based on a single publication of an enzyme from rabbit bone marrow that appears to be highly specific for guanosine and deoxyguanosine [YAMADA61]. Most enzymes that are known to catalyze this reaction, such as the human purine nucleoside phosphorylase, can accept other purines as well, and thus were attributed to a specific case of the more general enzyme EC 126.96.36.199, (guanosine + phosphate ↔ guanine + α-D-ribose-1-phosphate).
Instance reactions of [a purine ribonucleoside + phosphate ↔ a purine base + α-D-ribose-1-phosphate] (188.8.131.52):
i1: adenosine + phosphate ↔ α-D-ribose-1-phosphate + adenine (184.108.40.206)
i2: guanosine + phosphate ↔ α-D-ribose-1-phosphate + guanine (220.127.116.11)
i3: inosine + phosphate ↔ α-D-ribose-1-phosphate + hypoxanthine (18.104.22.168)
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