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Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Metabolic Modeling Tutorial
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Escherichia coli K-12 substr. MG1655 Reaction: 4.2.1.17

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 4.2.1.17

Enzymes and Genes:
predicted 2,3-dehydroadipyl-CoA hydratase Inferred by computational analysis : paaF

In Pathway: phenylacetate degradation I (aerobic)

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: enoyl-CoA hydratase

Enzyme Commission Synonyms: enoyl hydrase, unsaturated acyl-CoA hydratase, β-hydroxyacyl-CoA dehydrase, β-hydroxyacid dehydrase, hydratase, enoyl coenzyme A, acyl coenzyme A hydrase, crotonase, crotonyl hydrase, 2-octenoyl coenzyme A hydrase, enoyl coenzyme A hydratase, 2-enoyl-CoA hydratase, short-chain enoyl-CoA hydratase, ECH, trans-2-enoyl-CoA hydratase, enoyl coenzyme A hydrase (D), enoyl coenzyme A hydrase (L), short chain enoyl coenzyme A hydratase, D-3-hydroxyacyl-CoA dehydratase, enol-CoA hydratase

Enzyme Commission Summary:
Acts in the reverse direction. With cis-compounds, yields (3R)-3-hydroxyacyl-CoA. cf. EC 4.2.1.74 long-chain-enoyl-CoA hydratase.

Citations: [Moskowitz69, STERN57]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:4.2.1.17 , ENZYME:EC:4.2.1.17 , IUBMB-ExplorEnz:EC:4.2.1.17

Credits:
Created 05-Aug-2010 by Keseler I , SRI International


References

Moskowitz69: Moskowitz GJ, Merrick JM (1969). "Metabolism of poly-beta-hydroxybutyrate. II. Enzymatic synthesis of D-(-)-beta hydroxybutyryl coenzyme A by an enoyl hydrase from Rhodospirillum rubrum." Biochemistry 8(7);2748-55. PMID: 5808333

STERN57: STERN JR (1957). "Thioltranscrotonylase and beta-hydroxybutyryl COA racemase activities of crystalline crotonase." Biochim Biophys Acta 26(3);641-3. PMID: 13499425


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, biocyc12.