Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reaction: 3.1.13.1

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Macromolecule Reactions Polynucleotide-Reactions RNA-Reactions tRNA-Reactions

EC Number: 3.1.13.1

Enzymes and Genes:
RNase BN Inferred from experiment : rbn

Supersedes EC number: 3.1.4.20

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Undetermined; a substrate lacks a chemical formula

Enzyme Commission Primary Name: exoribonuclease II

Enzyme Commission Synonyms: ribonuclease II, ribonuclease Q, BN ribonuclease, Escherichia coli exo-RNase II, RNase II, exoribonuclease (misleading), 5'-exoribonuclease (misleading)

Enzyme Commission Summary:
Preference for single-stranded RNA. The enzyme processes 3′-terminal extra-nucleotides of monomeric tRNA precursors, following the action of EC 3.1.26.5 ribonuclease P.

Citations: [Sporn69, Shimura78, Schmidt78, Nossal68]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:3.1.13.1 , ENZYME:EC:3.1.13.1 , IUBMB-ExplorEnz:EC:3.1.13.1

Credits:
Created 20-Aug-2010 by Shearer A , SRI International


References

Nossal68: Nossal NG, Singer MF (1968). "The processive degradation of individual polyribonucleotide chains. I. Escherichia coli ribonuclease II." J Biol Chem 243(5);913-22. PMID: 4867942

Schmidt78: Schmidt FJ, McClain WH (1978). "An Escherichia coli ribonuclease which removes an extra nucleotide from a biosynthetic intermediate of bacteriophage T4 proline transfer RNA." Nucleic Acids Res 5(11);4129-39. PMID: 364422

Shimura78: Shimura Y, Sakano H, Nagawa F (1978). "Specific ribonucleases involved in processing of tRNA precursors of Escherichia coli. Partial purification and some properties." Eur J Biochem 86(1);267-81. PMID: 350582

Sporn69: Sporn MB, Lazarus HM, Smith JM, Henderson WR (1969). "Studies on nuclear exoribonucleases. 3. Isolation and properties of the enzyme from normal and malignant tissues of the mouse." Biochemistry 8(4);1698-706. PMID: 5805304


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Thu Dec 18, 2014, biocyc12.