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Escherichia coli K-12 substr. MG1655 Reaction: 3.1.27.6

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Macromolecule Reactions Polynucleotide-Reactions RNA-Reactions

EC Number: 3.1.27.6

Enzymes and Genes:
RNase I, cleaves phosphodiester bond between any two nucleotides Inferred from experiment : rna

Reaction Locations: periplasmic space (sensu Gram-negative Bacteria)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balance undetermined; a substrate lacks a chemical formula

Enzyme Commission Primary Name: Enterobacter ribonuclease

Enzyme Commission Summary:
Preference for cleavage at CpA. Homopolymers of A, U or G are not hydrolysed.

Citations: [Spahr61, Levy70, Marotta73]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:3.1.27.6 , ENZYME:EC:3.1.27.6 , IUBMB-ExplorEnz:EC:3.1.27.6

Credits:
Created 20-Aug-2010 by Shearer A , SRI International


References

Levy70: Levy CC, Goldman P (1970). "Residue specificity of a ribonuclease which hydrolyzes polycytidylic acid." J Biol Chem 245(12);3257-62. PMID: 5432809

Marotta73: Marotta CA, Levy CC, Weissman SM, Varricchio F (1973). "Preferred sites of digestion of a ribonuclease from Enterobacter sp. in the sequence analysis of Bacillus stearothermophilus 5S ribonucleic acid." Biochemistry 12(15);2901-4. PMID: 4719125

Spahr61: Spahr PF, Hollingworth BR (1961). "Purification and Mechanism of Action of Ribonuclease from Escherichia coli Ribosomes." J Biol Chem 236: 823-31.


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Tue Sep 1, 2015, biocyc13.